Efficacy of chemical treatments against murine norovirus, feline calicivirus, and MS2 bacteriophage

Foodborne Pathogens and Disease
Doris H D'Souza, Xiaowei Su

Abstract

Human noroviruses pose an emerging public health threat, and despite stringent control strategies, variant strains continue to spread and cause disease outbreaks. Routinely used chemical sanitizers, such as sodium hypochlorite though effective on food contact surfaces, require high concentrations to cause reduction in enteric viral titers. The aim of this study was to evaluate the efficacy of trisodium phosphate (TSP) against three human enteric virus surrogates, murine norovirus (MNV-1), feline calicivirus (FCV), and bacteriophage MS2 in comparison to routinely used sanitizers. Three concentrations of TSP (1%, 2%, and 5%) at different contact times (30 sec and 1 min) were evaluated against the surrogate viruses individually inoculated on formica coupons. Our results showed that 5% TSP was effective in obtaining a >or=6 log(10) PFU reduction for MNV-1, FCV, and MS2 after a contact time of only 30 sec or 1 min similar to 10% household bleach (0.6% sodium hypochlorite, 5000 ppm available chlorine) for high titers of FCV and MS2, and with approximately 5 log(10) reduction after either 30 sec or 1 min on low viral titers. However, 2% TSP for 1 min resulted in >or=6 log(10) PFU reduction for FCV and MS2, but only a 1.05 log(10) PFU ...Continue Reading

References

Nov 1, 1990·Applied and Environmental Microbiology·J N MbithiS A Sattar
Aug 1, 1986·The Journal of Hygiene·N Lloyd-EvansS A Sattar
Nov 22, 1997·FEMS Microbiology Letters·F X AbadA Bosch
Feb 9, 1999·The Journal of Hospital Infection·J C DoultreeJ A Marshall
Mar 8, 2003·Science·Stephanie M KarstHerbert W Virgin
Dec 22, 2004·Journal of Applied Microbiology·J A TreeD N Lees
Jun 1, 1994·Applied and Environmental Microbiology·J Y MaillardA D Russell
Jan 31, 2006·American Journal of Infection Control·Yashpal S MalikSagar M Goyal
Mar 17, 2006·International Journal of Food Microbiology·Yashpal S Malik, Sagar M Goyal
May 16, 2006·Journal of Virology·Christiane E WobusHerbert W Virgin
Jul 5, 2006·International Journal of Environmental Research and Public Health·Paul B AllwoodSagar M Goyal
Mar 14, 2007·The Journal of Hospital Infection·J B HudsonM Petric
Jul 10, 2007·Applied and Environmental Microbiology·Lorenza Ferrero PoschettoRachel E Marschang
Jan 22, 2008·The Journal of Hospital Infection·S L S LagesS M Goyal
Apr 2, 2008·Applied and Environmental Microbiology·Gaël BelliotPierre Pothier
Jul 1, 2008·Applied and Environmental Microbiology·David R MacingaJames W Arbogast

❮ Previous
Next ❯

Citations

Jul 6, 2012·Environmental Monitoring and Assessment·Hugo Ramiro PomaViviana Andrea Mbayed
Feb 16, 2013·Food and Environmental Virology·Xiaowei Su, Doris H D'Souza
Jun 26, 2010·Foodborne Pathogens and Disease·Xiaowei SuDoris H D'Souza
Sep 3, 2010·Foodborne Pathogens and Disease·Xiaowei SuDoris H D'Souza
Mar 9, 2011·Foodborne Pathogens and Disease·Xiaowei Su, Doris H D'Souza
Jul 23, 2011·Foodborne Pathogens and Disease·Xiaowei SuDoris H D'Souza
Nov 2, 2012·Foodborne Pathogens and Disease·Katie Marie HormDoris Helen D'Souza
Feb 14, 2012·Applied and Environmental Microbiology·Kristen E GibsonSteven C Ricke
Feb 7, 2014·The Journal of Antimicrobial Chemotherapy·Jordan MeyersRichard Robison
Sep 6, 2012·International Journal of Health Care Quality Assurance·Anja GerhardtsDirk Höfer
May 1, 2013·Food Microbiology·Dan LiMieke Uyttendaele
Jun 25, 2015·Journal of Applied Microbiology·S E Arthur, K E Gibson
May 23, 2012·Food Microbiology·Min Hwa LeeChangsun Choi
Nov 25, 2014·Food and Environmental Virology·Allison VimontJulie Jean
Nov 4, 2016·Food and Environmental Virology·Snehal S JoshiDoris H D'Souza
Oct 22, 2016·International Journal of Food Microbiology·Daseul ParkJiyong Park
Mar 10, 2018·International Journal of Molecular Sciences·Julia SommerPeter Rossmanith
Sep 10, 2017·Applied and Environmental Microbiology·Nathan DunkinKellogg J Schwab
Nov 8, 2011·Journal of Food Protection·Doris H D'SouzaFederico Harte
Jan 24, 2018·Journal of Food Protection·Alison LacombeHaiqiang Chen
Sep 10, 2014·Expert Review of Anti-infective Therapy·Eric J Ryndock, Craig Meyers
Apr 2, 2017·Scientific Reports·Xiuli DongLiju Yang
Mar 28, 2019·Food and Environmental Virology·Wenjun DengKristen E Gibson
May 8, 2021·Comprehensive Reviews in Food Science and Food Safety·Erdogan CeylanHeidy M W den Besten
Nov 19, 2021·Environmental Science & Technology·Bradley W SchmitzJoseph Jacangelo
May 23, 2020·American Journal of Infection Control·Karin GallandatDaniele S Lantagne
Sep 10, 2018·American Journal of Infection Control·Kelly A ReynoldsCharles P Gerba

❮ Previous
Next ❯

Methods Mentioned

BETA
Chemical Treatments

Software Mentioned

SAS

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.