Efficacy of conventional whole-body ¹⁸F-FDG PET/CT in the incidental findings of parotid masses

Annals of Nuclear Medicine
Hui-Chun WangYi-Hui Guan

Abstract

The objective of this study was to evaluate the incidence of incidental parotid masses with conventional whole-body ¹⁸F-deoxyglucose (FDG) PET/CT and assess the ability of PET/CT to characterize these unexpected parotid lesions. Fifty eight incidental findings of parotid masses with routine FDG PET/CT whole-body scan were reviewed in this retrospective analysis, which were selected from the patients without any known or suspected parotid disease in our PET center, from June 2005 to May 2009. 51 cases were operated or underwent a biopsy after a short-term PET/CT study; the remaining 7 cases had a follow-up. Parotid mass that showed both noncontrast CT (irregular shape and blurry border) and PET malignant features (high FDG uptake, SUV(max) > 3.0) was considered as positive for malignancy. Correlation of FDG PET/CT with histology or follow-up outcome was performed. Fifty eight unexpected findings of parotid masses accounted for 0.3% of the total cases in 4 years, including 11 (19.0%) malignant tumors and 47 (81.0%) benign lesions. 13 lesions manifested single nodule with malignant CT features and intense FDG activity, of which 6 were proved to be malignant; thus, sensitivity and positive predictive values were 54.5% (6 of 11) and...Continue Reading

References

Jul 1, 1994·Radiology·J W KeyesW F McGuirt
Jan 8, 1999·Acta Oto-laryngologica. Supplementum·T OkamuraY Nakai
Feb 22, 2005·Clinical Nuclear Medicine·Yoshitaka UchidaHisao Ito
Feb 24, 2005·European Journal of Nuclear Medicine and Molecular Imaging·C NanniS Fanti
Apr 29, 2005·Radiology·Barton F BranstetterCarolyn C Meltzer
Oct 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Joon Young ChoiByung-Tae Kim
Dec 14, 2005·Current Treatment Options in Oncology·Zoran RumboldtSusan Ackermann
Feb 24, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Einat Even-SapirUr Metser
Mar 3, 2007·The European Respiratory Journal·W De WeverJ Verschakelen
Sep 22, 2007·AJR. American Journal of Roentgenology·Vinil N Shah, Barton F Branstetter
Mar 4, 2008·American Journal of Otolaryngology·Ching-Chia LinShih-Tzu Huang
Mar 14, 2008·European Journal of Radiology·Y Y P LeeA T Ahuja
Jun 27, 2008·World Journal of Surgery·Chi Young LimCheong Soo Park
Jul 16, 2008·The British Journal of Oral & Maxillofacial Surgery·Krishnaraj Subhashraj
Aug 7, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Miraude AdriaensenJohn de Klerk
Oct 11, 2008·ANZ Journal of Surgery·Adele N Burgess, Jonathan W Serpell

❮ Previous
Next ❯

Citations

Sep 30, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Giorgio TregliaLuca Giovanella
Mar 5, 2016·Nuclear Medicine and Molecular Imaging·EunJung KongIhnHo Cho
Apr 19, 2015·Clinical Imaging·William MakisAkshat Gotra
May 29, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Christopher J BrittGregory K Hartig
Apr 7, 2011·Clinical Nuclear Medicine·Peeyush BhargavaJuliet Wendt
Jan 8, 2019·Nuclear Medicine Communications·Ramona-Rita BarbaraDavid Newman
Aug 20, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Achim M FranzenAnja Lieder
May 19, 2019·Annals of Nuclear Medicine·Marie Westergaard-NielsenKristine Bjørndal
Sep 22, 2020·Clinical Nuclear Medicine·Sofia C VazAntonio Galzerano
Mar 25, 2021·Head & Face Medicine·Hassan Al-BalasDavid M Sada
Jul 27, 2021·The Journal of Laryngology and Otology·Csg ThompsonM Bannister

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

ANZ Journal of Surgery
Jacob Ng, Tony Chan
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Carolin GrimmingerSimon F Preuss
© 2021 Meta ULC. All rights reserved