Efficacy of different load intensity and time-under-tension calf loading protocols for Achilles tendinopathy (the LOADIT trial): protocol for a randomised pilot study

Pilot and Feasibility Studies
Fatmah HasaniPeter Malliaras

Abstract

Modifying variables in exercise prescription can produce specific effects on Achilles tendinopathy outcomes. This study aims to determine the feasibility of conducting an adequately powered randomised trial in the future to assess the efficacy of different load intensity and time-under-tension exercise parameters for improving pain and function in individuals with persistent midportion Achilles tendinopathy. The trial is designed as prospective, four-armed feasibility and randomised pilot trial with 3 months follow-up. Interventions will be provided in a gym setting. The investigator, who will be blind to the allocation of participants, will conduct all pre- and post-intervention assessments. Forty-eight male participants with Achilles tendinopathy will be recruited from the community. We will use a 2 × 2 factorial design with factors of load intensity (six or eighteen repetitions maximum) and time-under-tension (two or six second repetitions). Participants will be randomised into one of the testing groups: six RM with two second repetitions, six RM with six second repetitions, eighteen RM with two second repetitions or eighteen RM with six second repetitions. Trial feasibility will be indicated by the rate of conversion, recru...Continue Reading

References

Dec 1, 1991·Journal of Applied Physiology·C T FarleyC R Taylor
Jan 1, 1985·American Journal of Epidemiology·J F SallisR S Paffenbarger
Oct 6, 1997·Foot & Ankle International·C Rolf, T Movin
Jun 9, 1998·The American Journal of Sports Medicine·H AlfredsonR Lorentzon
Aug 9, 2001·Annals of Medicine·R Rabin, F de Charro
Oct 2, 2001·British Journal of Sports Medicine·J M RobinsonUNKNOWN Victorian Institute Of Sport Tendon Study Group
May 4, 2005·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Urho M KujalaJaakko Kaprio
Jul 22, 2006·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Karin Grävare SilbernagelJon Karlsson
Aug 19, 2006·The Journal of Experimental Biology·Adamantios ArampatzisGert-Peter Brüggemann
Oct 7, 2006·Current Medical Research and Opinion·Rainer FreynhagenThomas R Tölle
Oct 13, 2006·British Journal of Sports Medicine·J J KingmaT Takken
Feb 22, 2007·British Journal of Sports Medicine·Håkan Alfredson, J Cook
Dec 19, 2008·Medicine and Science in Sports and Exercise·William G HopkinsJuri Hanin
Jul 14, 2009·Arthritis Research & Therapy·Michele AbateRoberto Paganelli
Jul 27, 2012·Scandinavian Journal of Medicine & Science in Sports·H-K WangY-C Huang
Jan 9, 2013·Annals of Internal Medicine·An-Wen ChanDavid Moher
Sep 13, 2013·Sports Medicine·Ebonie RioJill Cook
Sep 24, 2014·British Journal of Sports Medicine·Shannon E MunteanuHylton B Menz
May 29, 2015·The American Journal of Sports Medicine·Rikke BeyerS Peter Magnusson
Apr 1, 2017·Musculoskeletal Science & Practice·Sean Mc AuliffeKieran O'Sullivan
Mar 27, 2018·British Journal of Sports Medicine·Peter MalliarasChristian J Barton
May 2, 2018·The Journal of Orthopaedic and Sports Physical Therapy·Robroy L MartinChristopher R Carcia
Aug 17, 2018·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Michael L CeravoloRichard J Keegan

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Citations

Jan 15, 2021·BMJ Open·Adrian Escriche-EscuderAntonio I Cuesta-Vargas
May 10, 2021·Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine·Ian Burton, Aisling McCormack
Oct 26, 2021·PeerJ·Wesley MatthewsWayne A Hing

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