Efficacy of electrolyzed acid water in reprocessing patient-used flexible upper endoscopes: Comparison with 2% alkaline glutaraldehyde

Journal of Gastroenterology and Hepatology
Jun Haeng LeeNam Yong Lee

Abstract

Two percent glutaraldehyde, the most widely used liquid chemical germicide (LCG), may be hazardous to patients and medical personnel. Alternatives to glutaraldehyde, such as electrolyzed acid water (EAW), are being developed, but data from well-controlled studies with patient-used endoscopes are rare. The purpose of the present paper was to evaluate the high-level disinfection capability of EAW and compare it with glutaraldehyde. A random sample of 125 endoscopes was collected immediately after upper endoscopic examination. After careful manual cleaning, endoscopes were divided into a glutaraldehyde and EAW group. After the disinfection procedure, samples from working channel (S-1), insertion tube (S-2), umbilical cord (S-3), and angulation knob (S-4) were taken and cultured. Another twenty endoscopes were experimentally contaminated with hepatitis B virus (HBV) and samples were collected after contamination (T-1), after manual cleaning (T-2), and after final disinfection (T-3). Polymerase chain reaction (PCR) for HBV-DNA was performed. In the EAW group, culture-positive rates were 3.2% in S-1, 9.5% in S-2, 3.2% in S-3, and 27.0% in the S-4 samples. There was no significant difference between the EAW and glutaraldehyde groups f...Continue Reading

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Citations

Feb 9, 2008·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·O LeissM Exner
Apr 5, 2011·Journal of Bioscience and Bioengineering·Xinping ZengPing Li
Jan 3, 2015·Archives of Oral Biology·Takayuki MokudaiYoshimi Niwano
Jan 7, 2015·The Journal of Toxicological Sciences·Takayuki MokudaiYoshimi Niwano
Jun 30, 2005·Current Opinion in Infectious Diseases·Markus Dettenkofer, Colin Block
Jun 30, 2005·Current Opinion in Infectious Diseases·Douglas B Nelson
Aug 22, 2013·Clinical Endoscopy·Sanghoon ParkUNKNOWN Disinfection Management Committee, The Korean Society of Gastrointestinal Endoscopy
Jun 27, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Ryuichi IwakiriHisao Tajiri
Sep 25, 2008·Journal of Food Protection·D HricovaC Zweifel

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