Efficacy of flow- vs impedance-guided autoadjustable continuous positive airway pressure: a randomized cross-over trial

Chest
Dirk A PevernagieRomain A Pauwels

Abstract

Autoadjustable continuous positive airway pressure (CPAP) devices are increasingly used in the treatment of obstructive sleep apnea (OSA). Since different measurements of upper airway obstruction are applied, it is uncertain whether these devices are equally effective in controlling sleep-disordered breathing. Hypothesizing that differences in therapeutic efficacy were to come out, we compared the performance of the AutoSet device (ResMed; Sydney, Australia), which features autoadjustable positive airway pressure (APAP) guided by detection of flow limitation (APAPfl), with the SOMNOsmart device (Weinmann; Hamburg, Germany), which features APAP guided by the forced oscillation technique (APAPfot). A double-blind, randomized, cross-over trial. The sleep disorders center and sleep laboratory of a university hospital. An overnight CPAP autotitration procedure was performed in 30 patients with OSA. A split-night protocol allowed that each patient used both devices. Using polysomnography, sleep, indexes of sleep-disordered breathing, snoring, and CPAP levels were recorded. No significant differences were found in conventional sleep variables. While the apnea-hypopnea index (AHI) was lower with APAPfl (3.5 +/- 5.6/h) as compared to AP...Continue Reading

References

Jun 1, 1993·The American Review of Respiratory Disease·H Miljeteig, V Hoffstein
Dec 1, 1995·American Journal of Respiratory and Critical Care Medicine·J M MontserratR Rodriguez-Roisin
Sep 1, 1996·American Journal of Respiratory and Critical Care Medicine·H TeschlerN Konietzko
Dec 1, 1996·American Journal of Respiratory and Critical Care Medicine·P LloberesR Rodriguez-Roisin
Oct 6, 1997·The European Respiratory Journal·H TeschlerM Berthon-Jones
Nov 17, 1998·American Journal of Respiratory and Critical Care Medicine·A M LorinoH Lorino
Nov 11, 1999·American Journal of Respiratory and Critical Care Medicine·J R BadiaJ M Montserrat
Jul 8, 2000·The European Respiratory Journal·H TeschlerM Berthon-Jones
Jul 8, 2000·The European Respiratory Journal·D PevernagieR Pauwels
Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·W J RanderathK H Rühle

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Citations

Feb 20, 2013·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Takashi MurakamiShozo Kusachi
Sep 16, 2010·Current Opinion in Pulmonary Medicine·Lee K Brown
Jun 2, 2007·Respiration; International Review of Thoracic Diseases·Katrien B HertegonneDirk A Pevernagie
Jul 26, 2008·Respiratory Research·Frédéric SérièsYves Lacasse
Feb 6, 2008·Proceedings of the American Thoracic Society·Mark H SandersRachel J Givelber
Sep 1, 2006·Neuropsychiatric Disease and Treatment·Craig A Hukins
May 22, 2010·Clinics in Chest Medicine·Neil Freedman
Jul 24, 2007·Sleep Medicine·Winfried J Randerath
Apr 23, 2013·Respirology : Official Journal of the Asian Pacific Society of Respirology·Mario Francesco DamianiOnofrio Resta
Dec 7, 2010·Revue des maladies respiratoires·F PortierJ-C Meurice
Oct 13, 2009·The Cochrane Database of Systematic Reviews·Ian Smith, Toby J Lasserson

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