Efficacy of ICON® Maxx in the laboratory and against insecticide-resistant Anopheles gambiae in central Côte d'Ivoire.

Malaria Journal
Mirko S WinklerJürg Utzinger

Abstract

Long-lasting treatment kits, designed to transform untreated nets into long-lasting insecticidal nets (LLINs), may facilitate high coverage with LLINs where non-treated nets are in place. In this study, the efficacy of ICON® Maxx (Syngenta) was evaluated under laboratory conditions and in an experimental hut trial in central Côte d'Ivoire, where Anopheles gambiae s.s. are resistant to pyrethroid insecticides. In the laboratory, polyester and polyethylene net samples were treated with ICON® Maxx, washed up to 20 times and their efficacy determined in World Health Organization (WHO) cone assays against a susceptible laboratory An. gambiae s.s. colony. Over a 12-month period, the polyester nets were evaluated in a hut trial to determine mosquito deterrence, induced exophily, blood-feeding inhibition and mortality. In the laboratory, ICON® Maxx-treated polyethylene nets showed higher efficacy against pyrethroid-susceptible mosquitoes than polyester nets. After 20 washings, insecticidal efficacy in bioassays was 59.4% knockdown (KD) and 22.3% mortality for polyethylene, and 55.3% KD and 17.9% mortality for polyester nets. In experimental huts, treated nets showed strong deterrence, induced exophily and an over three-fold reduction i...Continue Reading

References

Apr 24, 2004·The Cochrane Database of Systematic Reviews·C Lengeler
Sep 28, 2005·Tropical Medicine & International Health : TM & IH·John E GimnigEllen M Dotson
Nov 3, 2005·Tropical Medicine & International Health : TM & IH·Kim A LindbladeJohn Gimnig
May 24, 2007·JAMA : the Journal of the American Medical Association·John M MillerRichard W Steketee
Dec 19, 2008·Malaria Journal·Joshua O YukichBrian Sharp
Apr 1, 2009·Malaria Journal·Joshua O YukichChristian Lengeler
Sep 17, 2009·Annual Review of Entomology·A Enayati, J Hemingway
Feb 12, 2011·PLoS Medicine·UNKNOWN malERA Consultative Group on Vector Control

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Citations

Apr 22, 2015·Methods in Ecology and Evolution·Paul C D JohnsonPie Müller

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Methods Mentioned

BETA
PCR

Software Mentioned

ICON
R
SLEEPER
lme4

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