Efficacy of inspiratory muscle training in chronic heart failure patients: a systematic review and meta-analysis

International Journal of Cardiology
Neil A SmartGudrun Dieberg

Abstract

Inspiratory muscle training (IMT) offers an alternative to exercise training (ExT) in the most severely deconditioned heart failure patients who are unable to exercise. We conducted a meta-analysis to determine magnitude of change in peak VO2, six minute walk distance (6MWD), Quality of Life measured by the Minnesota Living with Heart Failure Questionnaire (MLWHFQ), maximal inspiratory pressure (PI max) and ventilatory equivalent for carbon dioxide (VE/VCO2 slope) with IMT. A systematic search was conducted of randomized, controlled trials of IMT therapy in CHF patients using Medline (Ovid) (1950-February 2012), Embase.com (1974-February 2012), Cochrane Central Register of Controlled Trials and CINAHL (1981-February 2012). The search strategy included a mix of MeSH and free text terms for the key concepts heart failure, inspiratory or respiratory muscle training, exercise training The eleven included studies contained data on 287 participants: 148 IMT participants and 139 sham or sedentary control. Compared to control groups, CHF patients undergoing IMT showed a significant improvement in peak VO2 (+1.83 ml kg(-1) min(-1), 95% C.I. 1.33 to 2.32 ml kg(-1) min(-1), p<0.00001); 6 MWD (+34.35 m, 95% C.I. 22.45 to 46.24 m, p<0.00001...Continue Reading

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Citations

Nov 30, 2014·Heart Failure Clinics·Lawrence P Cahalin, Ross A Arena
Nov 17, 2015·Progress in Cardiovascular Diseases·Ross ArenaMarco Guazzi
Dec 17, 2014·Diabetes Research and Clinical Practice·Francesco GiallauriaUNKNOWN ISYDE-2008 Investigators of Italian Association for Cardiovascular Prevention, Rehabilitation (GICR-IACPR)
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Jan 22, 2015·Exercise and Sport Sciences Reviews·Lawrence P Cahalin, Ross Arena
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