Efficacy of intraoperative vancomycin in irrigating solutions on aqueous contamination during phacoemulsification.

Indian Journal of Ophthalmology
Renuka SrinivasanHarish Narasimha Belgode

Abstract

To study the efficacy of adding vancomycin in irrigating solutions, in comparison to topical antibiotic given preoperatively for a day, during phacoemulsification, in reducing the anterior chamber (AC) contamination. This was a prospective, interventional, hospital-based study. This was a study involving 400 eyes of 400 paitens, undergoing routine phacoemulsification between January 2004 and June 2006. The patients were non-randomly assigned to two groups: Group 1 included 180 patients, who received topical ciprofloxacin eye-drops (four-hourly) for a day preoperatively and Group 2 included 220 patients, who underwent phacoemulsification with vancomycin (20 microg/ml) in the irrigating solution. Anterior chamber aspirate obtained at the end of the surgery was sent for microbial workup. The number of positive cultures in both the groups was determined. This was performed using Chi-square test. Aqueous samples showed microbial growth in 38 (21.1%) out of 180 eyes in Group 1 and in 17 (7.7%) out of 220 eyes in Group 2 ( P = 0.001). Coagulase-negative staphylococcus was the most common organism in both the groups. Aqueous samples from four eyes in group 1 showed multiple organisms, while none of the sample from group 2 showed more t...Continue Reading

References

Feb 1, 1995·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·UNKNOWN Hospital Infection Control Practices Advisory Committee (HICPAC)
Sep 15, 1999·Ophthalmology·R Axer-SiegelD Weinberger
Jan 10, 2002·Clinical Microbiology Reviews·Michelle C CalleganMichael S Gilmore
Feb 28, 2002·The British Journal of Ophthalmology·G GallowayA Vivian
Apr 26, 2003·The British Journal of Ophthalmology·N MorletUNKNOWN teamEPSWA
Apr 3, 2004·American Journal of Ophthalmology·Christopher N TaHerminia Miño de Kaspar
Apr 7, 2005·Journal of Cataract and Refractive Surgery·José R VilladaJorge L Alió
Mar 28, 2006·Journal of Cataract and Refractive Surgery·David T L LiuDennis S C Lam
Apr 25, 2006·Journal of Cataract and Refractive Surgery·Peter BarryUNKNOWN ESCRS Endophthalmitis Study Group
Jul 27, 2007·Clinical & Experimental Ophthalmology·Arvind GuptaSajita Setia

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Citations

Mar 14, 2012·Journal of Ophthalmic Inflammation and Infection·Silvia RossettiMaría Alejandra Carrasco
Jun 3, 2014·BMC Ophthalmology·Jorge E Valdez-GarcíaJuan F Lozano-Ramírez
Dec 12, 2012·Journal of Cataract and Refractive Surgery·Bingsheng LouYizhi Liu
Oct 20, 2012·Current Opinion in Ophthalmology·Jayesh Vazirani, Sayan Basu
Sep 25, 2008·Journal of Cataract and Refractive Surgery·Takashi SuzukiYuichi Ohashi
Jan 1, 2012·Asia-Pacific Journal of Ophthalmology·Avinash PathengayHarry W Flynn
Jul 5, 2011·European Journal of Ophthalmology·Angelo BalestrazziMario Fruschelli

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