Efficacy of laparoscopic gastric bypass vs laparoscopic sleeve gastrectomy in treating obesity combined with type-2 diabetes.

British Journal of Biomedical Science
Y YanG Wang

Abstract

This prospective study compared the efficacy and safety of laparoscopic gastric bypass and laparoscopic sleeve gastrectomy in treating overweight and obese patients with BMI>28 kg/m2 and type-2 diabetes. Patients were randomized into a gastric bypass group (n = 77) or a gastrectomy group (n = 80). The surgery time, intraoperative blood loss, recovery time, and hospitalization time were collected. BMI, waistline, hipline, C-peptide level, insulin resistance index (HOMA-IR), and their blood and lipid profile were also measured. Surgery time and blood loss were significantly higher in the gastrectomy group, when compared to the gastric bypass group (P < 0.05). In both groups, the levels of BMI, waist circumference and hip circumference (but not their ratio) gradually and significantly decreased after surgery compared with baseline (P < 0.05), and no significant difference was found between these two groups. The C-peptide level, HOMA-IR, fasting blood glucose, 2-hour postprandial blood glucose and glycosylated haemoglobin gradually and significantly decreased after surgery compared with the values before treatment (P < 0.05). The levels of total cholesterol, triglyceride, LDL, and monocyte chemoattractant protein-1 were also lower ...Continue Reading

References

Oct 4, 2005·Lancet·David W Haslam, W Philip T James
Jan 29, 2010·Diabetes Care·UNKNOWN American Diabetes Association
Oct 27, 2010·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·B RokholmT I A Sørensen
May 23, 2012·American Journal of Preventive Medicine·Eric A FinkelsteinWilliam Dietz
Aug 1, 2014·CMAJ Open·Laurie K TwellsWilliam K Midodzi
Dec 5, 2014·PharmacoEconomics·Adela Hruby, Frank B Hu
Jul 19, 2016·Annals of Surgery·Magnus SundbomUNKNOWN Scandinavian Obesity Surgery Registry Study Group
Dec 28, 2016·International Journal of Molecular Sciences·Kyoung-Jin OhKwang-Hee Bae
Nov 28, 2017·International Journal of Surgery. Oncology·Maliha Agha, Riaz Agha
Feb 28, 2018·Pediatrics·Asheley Cockrell SkinnerSarah C Armstrong
Mar 24, 2018·JAMA : the Journal of the American Medical Association·Craig M HalesCynthia L Ogden

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