Efficacy of lifestyle and psychosocial interventions in reducing cognitive decline in older people: Systematic review.

Ageing Research Reviews
Emma WhittyClaudia Cooper

Abstract

It is unclear what non-pharmacological interventions to prevent cognitive decline should comprise. We systematically reviewed lifestyle and psychosocial interventions that aimed to reduce cognitive decline in healthy people aged 50+, and people of any age with Subjective Cognitive Decline or Mild Cognitive Impairment. We narratively synthesised evidence, prioritising results from studies rated as at lower Risk of Bias (ROB) and assigning Centre for Evidence Based Medicine grades. We included 64 papers, describing: psychosocial (n = 12), multi-domain (n = 10), exercise (n = 36), and dietary (n = 6) interventions. We found Grade A evidence that over 4+ months: aerobic exercise twice weekly had a moderate effect on global cognition in people with/ without MCI; and interventions that integrate cognitive and motor challenges (e.g. dance, dumb bell training) had small to moderate effects on memory or global cognition in people with MCI. We found Grade B evidence that 4+ months of creative art or story-telling groups in people with MCI; 6 months of resistance training in people with MCI and a two-year, dietary, exercise, cognitive training and social intervention in people with or without MCI had small, positive effects on global cogn...Continue Reading

References

Mar 1, 2008·British Journal of Sports Medicine·J G Z van UffelenM Hopman-Rock
Sep 5, 2008·JAMA : the Journal of the American Medical Association·Nicola T LautenschlagerOsvaldo P Almeida
Jan 27, 2010·Archives of Internal Medicine·Teresa Liu-AmbroseTodd C Handy
Apr 27, 2010·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Verena KlusmannFernando C Dimeo
Sep 18, 2010·Journal of Alzheimer's Disease : JAD·Laura D BakerSuzanne Craft
Dec 7, 2010·Neurobiology of Aging·Robert KrikorianDeborah J Clegg
Dec 16, 2010·International Journal of Geriatric Psychiatry·Naaheed MukadamGill Livingston
Feb 1, 2012·Journal of the American Geriatrics Society·Yohko MakiHaruyasu Yamaguchi
Dec 5, 2012·International Journal of Stroke : Official Journal of the International Stroke Society·Hege Ihle-HansenBrynjar Fure
Feb 27, 2013·Clinical Interventions in Aging·Timothy KwokFlorence Ho
Apr 16, 2013·Journal of the American Geriatrics Society·Rebecca Erwin WellsGloria Yeh
Jan 1, 2014·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·R Scott MackinPatricia A Arean
Apr 8, 2014·International Journal of Geriatric Psychiatry·Claudia CooperGill Livingston
Nov 20, 2014·Geriatrics & Gerontology International·Juliana Hotta Ansai, José Rubens Rebelatto
Nov 20, 2014·Journal of Alzheimer's Disease : JAD·Keri DiamondSharon L Naismith
Apr 4, 2015·Journal of Aging and Physical Activity·Jennifer N FogartyKevin T Hansen
May 12, 2015·JAMA Internal Medicine·Cinta Valls-PedretEmilio Ros
Aug 26, 2015·JAMA : the Journal of the American Medical Association·Kaycee M SinkUNKNOWN LIFE Study Investigators
Dec 30, 2015·The Journal of Clinical Endocrinology and Metabolism·Nidia Celeste HorieCintia Cercato
Jan 17, 2017·International Psychogeriatrics·Harris A EyreHelen Lavretsky
Jul 21, 2017·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Soon-Gook HongTae-Won Jun
Jul 25, 2017·Lancet·Gill LivingstonNaaheed Mukadam
Aug 26, 2017·American Journal of Alzheimer's Disease and Other Dementias·Ioulietta LazarouMagda Tsolaki
Oct 27, 2017·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Tze Pin NgKeng Bee Yap

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Citations

Dec 3, 2020·Nutrients·Tommaso FilippiniMarco Vinceti
Jan 23, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Christopher H GibbonsRoy Freeman
May 25, 2021·Acta Psychiatrica Scandinavica·Natalie ShohamClaudia Cooper
Aug 15, 2021·Translational Neurodegeneration·Miao XuNan-Jie Xu
Aug 20, 2021·Pilot and Feasibility Studies·Rosie EsseryLucy Yardley

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