Efficacy of liver parenchymal enhancement and liver volume to standard liver volume ratio on Gd-EOB-DTPA-enhanced MRI for estimation of liver function

European Radiology
Tomohide YoneyamaMasayuki Nakajo

Abstract

We aimed to develop and assess the efficacy of a liver function index that combines liver enhancement and liver volume to standard liver volume (LV/SLV) ratio on gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MRI. In all, 111 patients underwent a Gd-EOB-DTPA-enhanced MRI, including T1 mapping, before and 20 min after Gd-EOB-DTPA administration. We calculated the following Gd-EOB-DTPA-enhanced MRI-based liver function indices: relative enhancement of the liver, corrected enhancement of the liver-to-spleen ratio, LSC_N20, increase rate of the liver-to-muscle ratio, reduction rate of T1 relaxation time of the liver, ΔR1 of the liver and K Hep; the indices were multiplied by the LV/SLV ratio. We calculated the correlations between an indocyanine green (ICG) clearance and the Gd-EOB-DTPA-enhanced MRI-based liver function indices multiplied by the LV/SLV ratio, by using Pearson correlation analysis. There were significant correlations between all Gd-EOB-DTPA-enhanced MRI-based liver function indices and ICG clearance (r = -0.354 to -0.574, P < 0.001). All Gd-EOB-DTPA-enhanced MRI-based liver function indices multiplied by the LV/SLV ratio (r = -0.394 to -0.700, P < 0.001) were more strongly correlat...Continue Reading

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Citations

Jul 19, 2015·European Radiology·Michael HaimerlPhilipp Wiggermann
Mar 19, 2014·Magnetic Resonance Imaging·Shigeru MatsushimaYoshitaka Inaba
May 7, 2016·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Hirofumi HataHiroki Miyatake
Jul 8, 2016·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Gou OgasawaraYuki Takato
Nov 27, 2015·BioMed Research International·Dai ShimamotoHiroshi Honda
Jan 28, 2017·Scientific Reports·Michael HaimerlPhilipp Wiggermann
Oct 24, 2018·Clinical Hemorheology and Microcirculation·Irene FuhrmannMichael Haimerl
Nov 20, 2016·Clinical Hemorheology and Microcirculation·M HaimerlE-M Jung
May 7, 2019·Canadian Journal of Gastroenterology & Hepatology·René HakoMartin Janičko
Nov 20, 2016·Journal of Magnetic Resonance Imaging : JMRI·Ahmed Ba-SsalamahBernard E Van Beers

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