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Efficacy of low-dose methotrexate in rheumatoid arthritis

The New England Journal of Medicine

Mar 28, 1985

M E WeinblattD E Trentham

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Abstract

Twenty-eight patients with refractory rheumatoid arthritis completed a randomized 24-week double-blind crossover trial comparing oral methotrexate (2.5 to 5 mg every 12 hours for three doses weekly) with placebo. The methotrexate group had significant reductions (P less than 0.01 as com...read more

Mentioned in this Paper

HLA-DR2 Antigen
Erythrocyte Sedimentation Rate Measurement
Rheumatoid Arthritis
Transaminases
Nausea
HLA-DR Antigens
Immune-Associated Antigens
Clinical Trials
Methotrexate
Arthralgia
3
96
Paper Details
References
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12
  • References15
  • Citations360
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Efficacy of low-dose methotrexate in rheumatoid arthritis

The New England Journal of Medicine

Mar 28, 1985

M E WeinblattD E Trentham

PMID: 3883172

DOI: 10.1056/nejm198503283121303

Abstract

Twenty-eight patients with refractory rheumatoid arthritis completed a randomized 24-week double-blind crossover trial comparing oral methotrexate (2.5 to 5 mg every 12 hours for three doses weekly) with placebo. The methotrexate group had significant reductions (P less than 0.01 as com...read more

Mentioned in this Paper

HLA-DR2 Antigen
Erythrocyte Sedimentation Rate Measurement
Rheumatoid Arthritis
Transaminases
Nausea
HLA-DR Antigens
Immune-Associated Antigens
Clinical Trials
Methotrexate
Arthralgia
3
96

Feeds With Similar Papers

General Medical Journal eTOCs

Discover the latest medical research in this collection of the top medical journals.

NEJM eTOC

The New England Journal of Medicine (NEJM) is a medical journal published by the Massachusetts Medical Society. Discover the latest research from NEJM here.

Related Papers

Paper Details
References
  • References15
  • Citations360
12
  • References15
  • Citations360
12345...

Download from

Publisher
PubMed
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