Efficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars-A randomized controlled trial

Journal of Cosmetic Dermatology
Shiwangi RanaRam Chander

Abstract

Microneedling with dermaroller and glycolic acid peels is commonly used for treatment of acne scars. To compare efficacy of microneedling alone versus combination of microneedling with serial 70% glycolic acid peel in management of atrophic acne scars. Sixty patients with atrophic acne scars were randomized into group 1 receiving microneedling at 0, 6, and 12 weeks and group 2 receiving microneedling at 0, 6, and 12 weeks along with 70% glycolic acid peel at 3, 9, and 15 weeks. Acne scar scoring was performed by a blinded observer using ECCA (Echelle d'evaluation clinique des cicatrices d'acne) scoring at baseline and after 22 weeks. Additionally, patients were asked to grade the improvement in acne scars and skin texture on visual analogue scale (VAS). Of 60 patients, 52 completed the 22-week study period. The decrement from baseline in mean ECCA score was more in group 2 as compared to group 1 (39.65±2.50 vs 29.58±0.18; P<.001). Group 2 also showed more improvement in skin texture as compared to group 1 on VAS. Addition of sequential 70% glycolic acid peel to microneedling gives better scar improvement as compared to microneedling alone. In addition to this, it also improves skin texture.

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Citations

Dec 4, 2019·Plastic and Reconstructive Surgery·Tina S Alster, Monica Ka Yi Li
Jul 30, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Nisma MujahidNeelam A Vashi
Sep 10, 2019·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Basma AliNashwa Naeem Elfar
Jul 1, 2020·Journal of Cosmetic Dermatology·Alessia VillaniGabriella Fabbrocini
Jan 28, 2020·Plastic and Reconstructive Surgery·Tina S Alster, Monica Ka Yi Li
Feb 5, 2021·International Wound Journal·Irma Bernadette S SitohangJose Suryanegara
Dec 31, 2020·Clinical, Cosmetic and Investigational Dermatology·Margit L W Juhasz, Joel L Cohen
Aug 28, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Sherman ChuNatasha Atanaskova Mesinkovska

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