Efficacy of MR vs CT in epilepsy

AJR. American Journal of Roentgenology
E R HeinzW T Djang

Abstract

We studied 59 seizure patients with CT, MR, and EEG to determine the efficacy of each in the detection of an epileptogenic focus. EEG was most sensitive (67%), MR was next (53%), and CT was least sensitive (42%). MR detected an abnormality in five patients (8%) in whom CT was negative. EEG was positive in each of these patients. CT failed to demonstrate any focal lesion not detected by MR. MR and CT detected focal abnormalities in seven patients (12%) who had negative EEGs. Five of the seven patients had brain tumors. Eighteen of the 26 patients who underwent surgery had positive CT and MR; 14 of these patients had tumors. The remaining eight patients who had surgery all had temporal lobectomies for intractable seizures; none had tumors. In the complex partial seizure subgroup of 34 patients, MR was positive in 44%, CT was positive in 29%, and EEG was positive in 80%. We consider MR to be the imaging procedure of choice for the detection of an epileptogenic focus in seizure patients. When indicated, CT may be performed as a second procedure to try to distinguish neoplasm from thrombosed vascular malformations and other lesions.

Citations

Aug 1, 1990·Journal of Neuro-oncology·M C Chamberlain, G A Press
Jul 13, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ricardo Silva CentenoSergio Cavalheiro
Oct 1, 1989·Seminars in Roentgenology·R Lukin
Dec 1, 1994·Psychiatry Research·K J ShedlackK R Krishnan
Jan 1, 1997·Magnetic Resonance Imaging·R A BronenR C Lange
Jun 1, 1995·Seizure : the Journal of the British Epilepsy Association·S A Baxendale
Jan 15, 2014·Journal of Neurosurgery. Pediatrics·Timothy J KovandaAaron A Cohen-Gadol
Jan 23, 2014·Irish Journal of Medical Science·D A Olszewska, D J Costello
May 1, 2012·Epilepsy Research·Sabine G UijlCees A van Donselaar
Feb 7, 2012·CA: a Cancer Journal for Clinicians·Martha S LinetAmy Berrington de Gonzalez
Sep 1, 1994·Arquivos de neuro-psiquiatria·A CukiertR Marino Júnior
Apr 1, 1997·Clinical EEG (electroencephalography)·S K VelioğluS S Komsuoğlu
Oct 10, 2018·AJR. American Journal of Roentgenology·Eric TranvinhMax Wintermark
Jan 1, 1996·Epilepsia·G L Holmes
Aug 7, 2007·Expert Review of Neurotherapeutics·Fergus J Rugg-Gunn

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.