PMID: 8972429Dec 1, 1996Paper

Efficacy of nuclear scintigraphy in the diagnosis and management of sinusitis

The Journal of Otolaryngology
A R JaverA M Jafar

Abstract

The purpose of this study was to determine whether or not nuclear scintigraphy is useful in the diagnosis and management of chronic sinusitis. The ideal isotope(s) and drawbacks of the different isotopes in different clinical situations are reviewed and discussed. A retrospective review of patients undergoing nuclear medicine studies to aid in the diagnosis and management of sinus disease was carried out. Ideal candidates were chosen from both previously operated and unoperated patients whose computed tomography (CT) scan findings could not differentiate benign mucosal thickening from active inflammation. Nuclear scintigraphy scans using indium (In-111), gallium (Ga-67), and technetium (Tch-99m) were used to differentiate acute infection from chronic inflammation involving bone (osteitis) and/or mucosa. This information was then used to guide the management of their condition. Nuclear scintigraphy results were compared to findings on CT scan and during surgery. In-111 was found to be the best isotope for identifying pus or acute disease in the sinuses whereas Ga-67 was very good for identifying both chronic mucosal disease as well as acute disease. Tch-99m was very sensitive for identifying bony remodelling and was therefore no...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

BMJ : British Medical Journal
K L Evans
Current Medicine and Drugs
V R McCready
© 2021 Meta ULC. All rights reserved