Efficacy of Postoperative Antimicrobial Use for Clean Orthopedic Implant Surgery in Dogs: A Prospective Randomized Study in 100 Consecutive Cases

Veterinary Surgery : VS
Andrea PratesiThomas W Maddox

Abstract

To investigate whether administration of postoperative oral antimicrobial drugs has a beneficial effect on preventing surgical site infections (SSI) in clean orthopedic surgery involving stainless steel plating systems. Randomized prospective clinical study. Dogs (n = 97). One hundred consecutive cases (97 dogs) that had clean orthopedic surgery requiring stainless steel plate fixation were randomly assigned using a random number generator to either YES group (administration of postoperative oral antimicrobials) or NO group (no administration of postoperative oral antimicrobials). Dogs in YES group were administered oral cefalexin or potentiated amoxicillin for 7 days, whereas dogs in NO group were discharged without oral antibiotics. Minimum follow-up was 12 months. Multivariable logistic regression was used to determine risk factors for SSI. Overall postoperative infection rate was 12.9%. Infection occurred in 2 cases (4.3%) administered postoperative oral antimicrobials and in 10 cases (21.3%) not administered postoperative antimicrobials. Total anesthetic time and use of oral antimicrobials were the only significant factors associated with SSI. Use of postoperative antimicrobials was associated with a significant reduction ...Continue Reading

References

Oct 1, 1992·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·T C HoranT G Emori
Jan 1, 1993·Archives of Surgery·C P PageD H Wittmann
Jun 12, 1998·The Australian and New Zealand Journal of Surgery·M McDonaldA Forbes
Jul 1, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Dale W BratzlerUNKNOWN Surgical Infection Society
Sep 15, 2004·Veterinary Surgery : VS·Simone EugsterPatrick Boerlin
Jul 15, 2005·International Journal of Systematic and Evolutionary Microbiology·Luc A DevrieseFreddy Haesebrouck
Dec 6, 2005·The Surgical Clinics of North America·Philip S Barie, Soumitra R Eachempati
Jul 5, 2006·Journal of the American Veterinary Medical Association·J Scott Weese, Krista B Halling
Nov 27, 2007·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·S A Corr, C Brown
Dec 19, 2007·The Journal of Small Animal Practice·S P RochW M McKee
Oct 21, 2009·Journal of Materials Science. Materials in Medicine·T Fintan MoriartyR Geoff Richards
Oct 31, 2009·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·M G Ness
Jan 15, 2010·The Journal of Small Animal Practice·Anke Langenbach, Denis J Marcellin-Little
Mar 30, 2010·Veterinary Surgery : VS·Noel Fitzpatrick, Miguel Angel Solano
Jul 28, 2011·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·M GatineauM Moreau
Aug 14, 2012·Veterinary Surgery : VS·Noel FitzpatrickIan G Holsworth
Nov 23, 2012·The Australasian Medical Journal·Ru Shing Ng, Chee Ping Chong

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Citations

Jul 19, 2018·Journal of the American Veterinary Medical Association·Daniel J LopezGalina M Hayes
Feb 2, 2019·Veterinary Surgery : VS·Brandy A Burgess
Nov 3, 2017·Veterinary Surgery : VS·Danielle N Garcia Stickney, Kelley M Thieman Mankin
May 2, 2020·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·Darren R CarwardineKevin J Parsons
Mar 13, 2021·Veterinary Surgery : VS·Steven C BudsbergGabriella S Sandberg
Apr 28, 2021·Research in Veterinary Science·J StetterA Bergström

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