Efficacy of radical hysterectomy as treatment for patients with small cell carcinoma of the cervix

Cancer
B U SevinH E Averette

Abstract

This study was performed to identify pathologic and clinical features that best predict disease free survival of patients with early stage small cell carcinoma of the cervix treated by radical hysterectomy. Three hundreds and seventy patients with cervical carcinoma were analyzed retrospectively to define those variable that best predict disease free survival (DFS). Variables included age, weight, race, marital status, economic status, tumor size, depth of invasion (DI), lymph-vascular space involvement (LVSI), cell type, tumor grade, lymph node metastasis (LNM), and total number of lymph nodes removed. Patients with lymph node metastasis, parametrial involvement, and positive or close surgical margins were offered postoperative radiation. Twelve patients were found to have small cell carcinoma (3.2%). One patient had microinvasive carcinoma of the cervix (MIC) as defined by the Society of Gynecologic Oncologists with a depth of invasion of 3 mm or less and no lymph-vascular space invasion, and has been reported previously. A detailed analysis of the other patients with nonsmall cell carcinoma is presented separately. Five patients achieved a DFS of at least 5 years, whereas 7 patients died with disease. Excluding the patient w...Continue Reading

References

Oct 15, 1992·Cancer·B U SevinB Lampe
Jul 1, 1991·Gynecologic Oncology·B MillerG Photopulos
Nov 1, 1991·Gynecologic Oncology·K A O'HanlanL Rodriguez-Rodriguez
Jan 1, 1985·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·P GrobenF Askin
Oct 15, 1988·Cancer·J R van NagellE J Pavlik

❮ Previous
Next ❯

Citations

Dec 28, 2012·The Tohoku Journal of Experimental Medicine·Hideki TokunagaNobuo Yaegashi
Jul 25, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·S ShethS Arneja
Jan 31, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Reem AbdallahMian M K Shahzad
Jun 3, 2008·Obstetrics and Gynecology·Jergin ChenDavid K Gaffney
Sep 28, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·T KasamatsuM Tanikawa
Oct 9, 2008·The Journal of Obstetrics and Gynaecology Research·Tsuyoshi OtaKatsuyuki Kinoshita
Feb 24, 2001·Clinical Oncology : a Journal of the Royal College of Radiologists·S DelalogeC Lhommé
Jun 29, 2010·American Journal of Obstetrics and Gynecology·Joshua G CohenJohn K Chan
May 8, 1998·Gynecologic Oncology·R E EstapeH Averette
Jun 28, 2001·Gynecologic Oncology·A BermúdezJ Sardi
May 25, 2011·Journal of Gynecologic Oncology·Hyun Jong ParkYoung Tae Kim
Jul 29, 2016·Current Opinion in Oncology·Nicholas S Reed
May 4, 1999·Seminars in Surgical Oncology·B U Sevin
Apr 22, 2004·AJR. American Journal of Roentgenology·Dong Hyun YangKyoung-Sik Cho
May 6, 2008·The Journal of Emergency Medicine·Ariel Eric KlevanVincent Y T Cheung
Jan 10, 2014·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Suthida IntaraphetJayanton Patumanond
Jun 16, 2004·Archives of Gynecology and Obstetrics·Edgar PetruG Breitenecker
Apr 9, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Shin Wha LeeYoung-Tak Kim
Nov 11, 2010·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Jie LiuHuiping Zhang
Aug 1, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Changlong HouShiting Feng
Jun 24, 2003·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Yuichiro SatoTohru Hayashi
Nov 26, 2019·The Pan African Medical Journal·Kaoutar RaisTijani El Harroudi
Jul 24, 2012·Current Opinion in Oncology·Joshua G CohenDaniel S Kapp
Feb 9, 2012·Clinical Nuclear Medicine·Te-Chun HsiehChia-Hung Kao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.