Abstract
Chemotherapy-induced alopecia (CIA) is a distressing adverse effect of many chemotherapy agents. The TC (docetaxel [Taxotere] and cyclophosphamide) chemotherapy regimen is typically associated with complete alopecia. Scalp cooling with cold caps has been reported to minimize or prevent CIA. We conducted a prospective study to assess efficacy of scalp cooling in preventing CIA among women receiving adjuvant TC chemotherapy for breast cancer. Women at the Weill Cornell Breast Center who independently elected to use scalp cooling with cold caps during adjuvant TC chemotherapy were asked to participate. Degree of hair loss was assessed by a single practitioner using Dean's alopecia scale (grade 1/excellent [< 25% hair loss], grade 2/good [25%-50% hair loss], grade 3/moderate [50%-75% hair loss], grade 4/poor [> 75% hair loss]), by digital photographs, and by patient self-report of hair thinning or the need to wear a wig/head covering, or both. Assessments were made before each chemotherapy treatment and at follow-up visits between 3 weeks and 3 months after completion of chemotherapy. Of 20 evaluable patients, 10% reported a need to wear a wig/head covering at the follow-up visit. Dean's alopecia score was excellent for 65% of pati...Continue Reading
References
Jun 1, 1988·Cancer Nursing·G GiacconeA Calciati
May 1, 1987·Journal of Advanced Nursing·A J Tierney
Feb 7, 1981·British Medical Journal·J E AndersonI E Smith
Aug 5, 1995·Lancet·M LemenagerJ Bonneterre
Jan 1, 1994·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R A TollenaarC J van de Velde
Mar 1, 1997·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·I G RonS Chaitchik
Mar 27, 2002·Oncology·C ChristodoulouD V Skarlos
Jul 12, 2002·Psycho-oncology·Benji BenjaminTimothy Meakin
Jul 13, 2002·Cancer·Nadége CarelleDavid Khayat
Sep 27, 2002·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Christel ProtièreDominique Genre
May 13, 2006·Annals of Oncology : Official Journal of the European Society for Medical Oncology·W Breed
Feb 26, 2009·Breast Cancer Research and Treatment·Julie LemieuxElizabeth Maunsell
Mar 25, 2011·Breast Cancer Research and Treatment·Julie LemieuxJean-Charles Hogue
Feb 7, 2012·Acta Oncologica·Corina J van den HurkWim P Breed
May 26, 2012·International Journal of Trichology·Dilip Gude
Citations
Oct 7, 2016·The Journal of Dermatology·Myungsoo JunWon-Soo Lee
Oct 5, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·V V ShahJ J Jimenez
May 28, 2016·British Journal of Nursing : BJN·Annie Young, Azra Arif
Jul 13, 2018·Future Oncology·Mollie M MustoeHope S Rugo
Nov 2, 2018·JAMA Dermatology·Dustin H MarksAdam Friedman
Nov 21, 2018·Reviews on Recent Clinical Trials·Tiziana ProchiloAlberto Zaniboni
Sep 13, 2019·EMBO Molecular Medicine·Talveen S PurbaRalf Paus
Mar 10, 2017·Chronobiology International·Armiya SultanArti Parganiha
Jan 4, 2019·Indian Journal of Cancer·Marniza SaadAdlinda Alip
Sep 28, 2017·The Oncologist·Christopher John DunnillNikolaos Theodoros Georgopoulos
Jun 28, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jung-Woo ChaeAlexandre Chan
Sep 19, 2017·Breast Cancer Research and Treatment·Brooke A RiceMichelle E Melisko
Jan 9, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·WeiLian CongChunLan Zhou
Dec 23, 2020·European Journal of Cancer Care·Joachim ChanNicola Thorp
Jul 20, 2020·The Journal of Investigative Dermatology·Iain S HaslamZhiCao Yue
Mar 27, 2021·Carbohydrate Polymers·Cuiping LiLirong Han
Apr 14, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Shurui WangFangyuan Zhang
Jul 2, 2019·Asia-Pacific Journal of Oncology Nursing·Emilia GianottiFabrizio Artioli