Efficacy of selamectin against adult flea infestations (Ctenocephalides felis felis and Ctenocephalides canis) on dogs and cats

Veterinary Parasitology
T L McTierA D Jernigan

Abstract

Selamectin was evaluated in eight controlled studies (4 in dogs, 4 in cats) to determine the efficacy of a single topical unit dose providing the recommended minimum dosage of 6mgkg(-1) against Ctenocephalides felis felis and Ctenocephalides canis fleas on dogs and against C. felis on cats. In addition, the effect of bathing on the efficacy of selamectin against C. felis was evaluated. Identical studies were performed in Beagles and domestic shorthaired cats. For each study, animals were allocated randomly to treatments of 8-12 animals each. All studies (dog studies A, B, C, and D and cat studies A, B, C, and D) evaluated the efficacy of selamectin without bathing. In addition, study C in both dogs and cats evaluated efficacy with a shampoo bath at 24h after dosing, and study D evaluated the efficacy of selamectin with water soaking at 2h after dosing or with a shampoo bath at 2-6h after dosing. Dog study B evaluated efficacy against C. canis, whereas all other studies used C. felis. In each study, selamectin was administered on day 0 as a topical dose that was applied directly to the skin in a single spot at the base of the neck in front of the scapulae. Dogs and cats were infested with approximately 100 viable unfed C. felis ...Continue Reading

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Citations

Nov 27, 2008·Acta Veterinaria Scandinavica·Maggie A Fisher, David J Shanks
Aug 9, 2003·Journal of the American Veterinary Medical Association·Tom L McTierLeland Thompson
Apr 30, 2016·Case Reports in Radiology·Taylor RisingPauravi Vasavada
Dec 21, 2012·Journal of Feline Medicine and Surgery·Meng Siak, Mandy Burrows
Mar 11, 2003·The Veterinary Record·D J ShanksT G Rowan

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