Efficacy of selected anthelmintic drugs against cyathostomins in horses in the federal state of Brandenburg, Germany

Parasitology Research
Juliane K FischerPeter-Henning Clausen

Abstract

Cyathostomins are currently the most common internal parasites of horses. With the intensive use of anthelmintic drugs over the past decades, resistance of cyathostomins to anthelmintics is becoming a growing problem in many countries. The aim of this study was to assess the current situation on horse farms in the German federal state of Brandenburg. A pre-selected population of horses from 24 premises that had shown a prevalence of cyathostomins higher than the average in a previous study was examined for anthelmintic efficacy. Faecal egg count reduction tests (FECRTs) were performed for ivermectin (IVM) and pyrantel (PYR). For IVM, the egg reappearance period (ERP) was also examined, as a shortened ERP can be indicative of developing resistance. The efficacy of IVM on cyathostomins was high: 99.1 % of 224 horses had a zero egg count 14 days after treatment. No shortening of the ERP was detected. For the data of the FECRT for PYR, three different methods of calculation were employed: (a) the method as recommended by the World Association for the Advancement of Veterinary Parasitology (WAAVP), (b) a bootstrapping method and (c) a Markov chain Monte Carlo method. Two methods of interpretation for these data were used: Resistance...Continue Reading

References

Jul 29, 1995·The Veterinary Record·S KochapakdeeA Lawpetchara
Oct 6, 1999·Journal of Medical Microbiology·G C Coles
Apr 2, 2002·The Veterinary Record·J H BoersemaJ W M Nas
Jun 25, 2002·Veterinary Parasitology·J F PookD R Hodgson
Oct 18, 2002·Veterinary Parasitology·Bryan O'Meara, Grace Mulcahy
Oct 22, 2002·Veterinary Research·Ray M Kaplan
Mar 3, 2005·Veterinary Parasitology·P R TorgersonH Hertzberg
Mar 25, 2008·The Veterinary Record·M B MolentoG C Coles
Dec 8, 2009·Preventive Veterinary Medicine·M J DenwoodG T Innocent
Apr 28, 2012·Veterinary Parasitology·Donato TraversaMelanie D'Espois
Jul 9, 2013·Veterinary Parasitology·H E LesterJ B Matthews
Dec 10, 2013·Veterinary Parasitology·M Lyndal-MurphyP M Pepper
Apr 22, 2014·International Journal for Parasitology·Valerie E RelfJacqueline B Matthews

❮ Previous
Next ❯

Citations

Nov 12, 2016·International Journal for Parasitology. Drugs and Drug Resistance·Miguel Peña-EspinozaHeidi L Enemark

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.