Efficacy of sleep position modification to treat positional obstructive sleep apnea

Sleep Medicine
Melinda JacksonMaree Barnes

Abstract

To assess the feasibility and efficacy of sleep position modification in preventing supine sleep and improving sleep-disordered breathing and relevant clinical outcomes in positional obstructive sleep apnea (OSA) patients. Eighty-six consecutive participants with moderate positional OSA on routine diagnostic polysomnography underwent a randomized controlled parallel group design trial of 4-weeks treatment using a sleep position modification device (active) or sleep hygiene advice (control). Outcomes were measured at baseline and following a 4-week treatment period. There was a significant reduction in the amount of supine sleep in the active group (mean ± SD change from baseline, active group 99.5 ± 85.2 minutes, control group 68.6 ± 103.2 minutes, p = 0.002), and an improvement in apnea-hypopnea index (AHI) (active group reduced by 9.9 ± 11.6, control group reduced by 5.3 ± 13.9, p = 0.013). Post-hoc analyses indicated that positional therapy was most effective for patients with baseline AHI cut-off above 20 (p = 0.02). Logistic regression showed that a treatment response (AHI < 10) was more likely in the active group (OR = 5.57), and those with higher baseline nadir oxygen desaturation (OR = 1.95) and non-supine AHI (OR = 0.5...Continue Reading

References

Feb 1, 1989·Australian and New Zealand Journal of Medicine·L A Bach, K Sharpe
Apr 29, 1993·The New England Journal of Medicine·T YoungS Badr
Jan 1, 1997·American Journal of Respiratory and Critical Care Medicine·A M NeillR D McEvoy
Feb 24, 2001·Psychiatry and Clinical Neurosciences·Y ItasakaK Togawa
Nov 10, 2001·BMJ : British Medical Journal·A J Vickers, D G Altman
Jun 14, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C ViolaniL Ferini Strambi
Mar 9, 2004·American Journal of Respiratory and Critical Care Medicine·W Ward FlemonsJohn Wheatley
Jun 18, 2004·American Journal of Respiratory and Critical Care Medicine·Maree BarnesRobert J Pierce
Sep 1, 2007·Acta Oto-laryngologica·Helena Loord, Elisabeth Hultcrantz
Aug 21, 2008·Respirology : Official Journal of the Asian Pacific Society of Respirology·Margot A SkinnerD Robin Taylor
Feb 11, 2011·Sleep Medicine·Anna SvatikovaDevin L Brown
Sep 8, 2011·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·James J BignoldPeter G Catcheside
Oct 25, 2011·Journal of Sleep Research·J Peter van MaanenNico de Vries
May 15, 2013·Sleep Medicine Reviews·Simon A JoostenGarun S Hamilton

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Citations

Aug 31, 2017·Sleep & Breathing = Schlaf & Atmung·Olabimpe Omobomi, Stuart F Quan
Jun 26, 2017·Sleep & Breathing = Schlaf & Atmung·Fábio José Fabrício de Barros SouzaGeraldo Lorenzi-Filho
May 2, 2019·The Cochrane Database of Systematic Reviews·P R SrijitheshJayaraj Dhanya
Jan 1, 2017·Expert Review of Precision Medicine and Drug Development·Manuel Sânchez-de-la-Torre, David Gozal
Dec 12, 2020·Nature and Science of Sleep·Himanshu GargSubash S Heraganahally
Apr 24, 2021·Thorax·Laura Hidalgo ArmasUNKNOWN Spanish Sleep Network

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