PMID: 16615668Apr 18, 2006Paper

Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study

Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists
M Misbahuddin Anjumanara

Abstract

Millions of people in Bangladesh, India, Taiwan, and Chile are consuming high concentration of arsenic through drinking water, and thousands of them have already developed chronic arsenic poisoning. There is no specific treatment. Some authors suggest the use of vitamins and minerals for more than 6 months. The present placebo-controlled double-blind study was conducted to evaluate effectiveness of spirulina extract plus zinc in the treatment of chronic arsenic poisoning. Forty-one patients of chronic arsenic poisoning were randomly treated orally by either placebo (17 patients) or spirulina extract (250 mg) plus zinc (2 mg) (24 patients) twice daily for 16 weeks. Each patient was supplied with arsenic-safe drinking water by installing a locally made water filter at household level. Effectiveness of spirulina extract plus zinc was evaluated by comparing changes in skin manifestations (clinical scores), arsenic contents in urine and hair, between the placebo- and spirulina extract plus zinc-treated groups. The concentrations of total arsenic in water (without filtration) of placebo- and spirulina extract plus zinc-treated groups were 150.1 +/- 18.3 and 161.7 +/- 23.9 microg/l, respectively. Intake of these high concentrations of...Continue Reading

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Citations

Jan 25, 2011·Journal of Medicinal Food·Norma Paniagua-CastroGermán Chamorro-Cevallos
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·P D KarkosD A Assimakopoulos
Sep 14, 2007·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Mir MisbahuddinMohammad Al-Amin
May 19, 2011·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·A K M YousufMd Sayedur Rahman
Apr 25, 2008·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Elias E MazokopakisEmmanuel S Ganotakis
Dec 26, 2006·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Kiran KaliaS J S Flora
Oct 7, 2015·Pharmaceutical Biology·Elizdath Martínez-GaleroGerman Chamorro
Apr 18, 2014·Nutrition Research and Practice·Weiqian ZhangZhigang Zhang

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