Efficacy of standardized sublingual immunotherapy of allergic asthma with rhinitis in children between different age groups

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
S J WuXia Zeng

Abstract

Objective:The aim of this study is to evaluate the efficacy of standardized sublingual immunotherapy of allergic asthma with rhinitis in children between two different age groups. Method:Retrospective analysis of 250 patients with allergic asthma and rhinitis who received SLIT treatment. According to the age divided into younger children group (aged 3-6 years, 128 patients) and older children group (aged 7-13 years, 122 patients). Evaluate the asthma daytime, nocturnal symptom, medication score, VAS score and pulmonary function FEV1, PEF% level and rhinitis symptom and medication score before and after treatment of two groups of children. Result:The DASS, NASS, TAMS, VAS, FEV1, PEF, TNSS, TRMS had continuously improved significantly after SLIT for half a year, 1 year and 2 years in two groups as compared with baseline (P<0.05). The treatment after 1 year and 2 years, curative effect strengthened continuously, and TAMS, VAS, TNSS and TRMS further reduced. After treatment of each point in time, only at SLIT treatment after half a year, the TAMS, VAS score of younger children group was lower than of older children group (Z values were 4.58 and 4.58, P<0.05). The rest of the indicators were no statistical significance difference be...Continue Reading

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