Efficacy of Viola odorata in Treatment of Chronic Insomnia

Iranian Red Crescent Medical Journal
Zohre FeyzabadiOmid Sadeghpour

Abstract

Insomnia is the most common sleep disorder that reduces quality of life. Due to side effects of hypnotic drug and the increasing demand for alternative medicine substitutes, violet oil (VO) was used in this study. VO is a known medication in Iranian traditional medicine that induces sleep in insomniac patients. This study was conducted as an experimental pretest-posttest evaluation on VO efficacy in 50 patients with chronic insomnia in Iranian Traditional Medicine Clinic of Mashhad University of Medical Sciences, Mashhad, Iran. Treatment consisted of intranasal drop of VO, two drops containing 66 mg of VO in each nostril nightly before sleeping for one month. All patients were asked to complete an Insomnia Severity Index (ISI) questionnaire before the start of the trial and after one month of treatment. Improvements in sleep and ISI scores were significantly greater in patients after a month receiving VO drop in comparison with before starting treatment (P < 0.05). A few patients reported some complications about VO consumption, most of which were mild and no serious adverse event was encountered. VO can be presented as a safe, well-tolerated, and effective herbal preparation in patients with chronic insomnia.

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Citations

May 9, 2015·Journal of Evidence-based Complementary & Alternative Medicine·Mohammad Javad QasemzadehMohammad Bagher Minae
May 10, 2018·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Maryam RanjbarAli Firoozabadi
Aug 5, 2017·BMC Complementary and Alternative Medicine·M KatochS N C Sridhar
Feb 20, 2020·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Maryam ShayestehFatemeh Heidary
Oct 9, 2019·Journal of Food and Drug Analysis·Cristina MolinerCarlota Gómez Rincón
Nov 1, 2020·Drug Metabolism and Personalized Therapy·Sana FatimaUNKNOWN Murtada Taha
Sep 24, 2020·Drug Metabolism and Personalized Therapy·Md Anzar AlamMariyam Ahad
Feb 6, 2021·Journal of Complementary & Integrative Medicine·Md Anzar AlamBangalore Nagaraj Renuka
Jun 12, 2021·Planta medica·Silvia BorrásJosé Luis Ríos
Jul 30, 2021·Frontiers in Pharmacology·Jasmin GattringerRoland Hellinger

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Methods Mentioned

BETA
pregnancy test
sedation
enzyme-linked immunosorbent assay

Software Mentioned

SPSS

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