Efficacy predictors of a 2-month exclusive enteral nutrition for inducing remission of active Crohn's disease

European Journal of Clinical Nutrition
Meng XueYan Chen

Abstract

In order to identify the factors that could predict the efficacy of exclusive enteral nutrition (EEN) in inducing remission of active CD. Baseline clinical and laboratory covariates were correlated with the outcome (clinical remission) of EEN in active CD (CDAI ≥150) by both univariable and multivariable analyses. A total of 67 from a consecutive of 136 active CD patients were enrolled. L4b (from treitz ligament to distal 1/3 ileum) involvement was negatively and high serum albumin (≥35 g/L) was positively associated with clinical remission (OR: 0.14, OR: 14.71). In conclusion, L4b sparing and high serum albumin might predict a favorable outcome of EEN in active CD (ClinicalTrials.gov ID: NCT 02942511).

References

Aug 1, 1994·Journal of Pediatric Gastroenterology and Nutrition·T RuuskaJ K Visakorpi
May 10, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Osvaldo BorrelliSalvatore Cucchiara
Aug 24, 2012·Lancet·Daniel C Baumgart, William J Sandborn
Nov 28, 2013·World Journal of Gastroenterology : WJG·Catherine L WallRichard B Gearry

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Citations

Jul 26, 2019·Alimentary Pharmacology & Therapeutics·Michael LoganRichard K Russell
Dec 17, 2020·Nutrients·Marta Herrador-LópezVíctor Manuel Navas-López

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