Efficient and regiospecific one-pot synthesis of substituted 1,2,4-triazoles

Organic Letters
Michael J StocksRachel Reynolds

Abstract

An efficient one-pot, three-component synthesis of substituted 1,2,4-triazoles has been developed, utilizing a wide range of substituted primary amines and acyl hydrazides.

Citations

Feb 3, 2009·Archives of Pharmacal Research·Cheng-Xi WeiZhe-Shan Quan
Jul 30, 2005·The Journal of Organic Chemistry·Amarnath NatarajanMichael Chorev
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Saira KhanumPeter G Jones
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Tanveer AhmadMasood Parvez
Jan 15, 2014·European Journal of Medicinal Chemistry·Xian-Qing DengZhe-Shan Quan
Mar 22, 2014·European Journal of Medicinal Chemistry·Bassem SadekHolger Stark
Jan 22, 2011·Chemical Biology & Drug Design·Dalip KumarKavita Shah
Nov 18, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·He TianGuilong Zhao
Mar 1, 2006·Bioorganic & Medicinal Chemistry Letters·Adrian HallRichard J Wilson
Jun 8, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Jinhui WangSuzanne Fery-Forgues
Feb 1, 2018·Journal of Enzyme Inhibition and Medicinal Chemistry·Ming-Xia Song, Xian-Qing Deng
Mar 7, 2019·Journal of Enzyme Inhibition and Medicinal Chemistry·Tian LuanZhe-Shan Quan
Oct 29, 2020·Chemical Communications : Chem Comm·Chunyan ZhangMao-Lin Hu
Oct 6, 2009·Journal of the American Chemical Society·Satoshi Ueda, Hideko Nagasawa
Jan 18, 2011·The Journal of Organic Chemistry·Georgette M CastanedoSteven T Staben
Aug 21, 2020·The Journal of Organic Chemistry·Juliana M de SouzaD Tyler McQuade
Nov 18, 2010·The Journal of Organic Chemistry·Yingju XuRobert A Reamer
Jan 8, 2015·The Journal of Organic Chemistry·Hao XuYanrong Ren
Aug 1, 2019·Journal of Agricultural and Food Chemistry·Hong-Yan GuoZhe-Shan Quan
Sep 5, 2018·The Journal of Organic Chemistry·Na Yang, Gaoqing Yuan

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