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Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages

bioRxiv

Mar 6, 2015

Mingwei MinCatherine Lindon

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Abstract

The ubiquitin proteasome system (UPS) directs programmed destruction of key cellular regulators via post-translational modification of its targets with polyubiquitin chains. These commonly contain Lysine 48 (K48)-directed ubiquitin linkages, but chains containing atypical Lysine 11 (K11...read more

Mentioned in this Paper

Mitotic Anaphase
Cobalt
Ligase
Lysine
Mitosis
Post-Translational Protein Processing
Ubiquitin
E-Cadherin
Ubiquitin-protein ligase
Polyubiquitin
8
26
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  • Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages

    bioRxiv

    Mar 6, 2015

    Mingwei MinCatherine Lindon

    PMID: 990016139

    DOI: 10.1101/016139

    Abstract

    The ubiquitin proteasome system (UPS) directs programmed destruction of key cellular regulators via post-translational modification of its targets with polyubiquitin chains. These commonly contain Lysine 48 (K48)-directed ubiquitin linkages, but chains containing atypical Lysine 11 (K11...read more

    Mentioned in this Paper

    Mitotic Anaphase
    Cobalt
    Ligase
    Lysine
    Mitosis
    8
    26

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