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Efficient Approach to Correct Read Alignment for Pseudogene Abundance Estimates

IEEE/ACM Transactions on Computational Biology and Bioinformatics

Jul 19, 2016

Chelsea J-T JuWei Wang

Abstract

RNA-Sequencing has been the leading technology to quantify expression of thousands of genes simultaneously. The data analysis of an RNA-Seq experiment starts from aligning short reads to the reference genome/transcriptome or reconstructed transcriptome. However, current aligners lack th...read more

Mentioned in this Paper

Study
Genome
Genes
RNA, Untranslated
Sequence Determinations, RNA
Log-Linear Models
Human RNA Sequencing
Genomics
Sequencing
Pseudogenes
6
27
Paper Details
References
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  • Citations
123
  • References21
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Efficient Approach to Correct Read Alignment for Pseudogene Abundance Estimates

IEEE/ACM Transactions on Computational Biology and Bioinformatics

Jul 19, 2016

Chelsea J-T JuWei Wang

PMID: 27429446

DOI: 10.1109/tcbb.2016.2591533

Abstract

RNA-Sequencing has been the leading technology to quantify expression of thousands of genes simultaneously. The data analysis of an RNA-Seq experiment starts from aligning short reads to the reference genome/transcriptome or reconstructed transcriptome. However, current aligners lack th...read more

Mentioned in this Paper

Study
Genome
Genes
RNA, Untranslated
Sequence Determinations, RNA
Log-Linear Models
Human RNA Sequencing
Genomics
Sequencing
Pseudogenes
6
27

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Structural Biology: Biophysics

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Chromosomal duplication is a result of extra genetic material within the area of the chromosome. The duplication may have no effect or may be expressed in the phenotype of that individual. Some duplications are thought to be of evolutionary selection. Discover the latest research on chromosomal duplication here.

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RNA-Seq gene profiling--a systematic empirical comparison

PloS OneOctober 1, 2014
Nuno A FonsecaAlvis Brazma
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TopHat: discovering splice junctions with RNA-Seq

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Paper Details
References
  • References21
  • Citations
123
  • References21
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
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