Efficient asymmetric transfer hydrogenation of ketones in ethanol with chiral iridium complexes of spiroPAP ligands as catalysts

Chemical Communications : Chem Comm
Wei-Peng LiuQi-Lin Zhou

Abstract

Highly efficient iridium catalyzed asymmetric transfer hydrogenation of simple ketones with ethanol as a hydrogen donor has been developed. By using chiral spiro iridium catalysts (S)- a series of alkyl aryl ketones were hydrogenated to chiral alcohols with up to 98% ee.

References

Jan 30, 2004·Journal of the American Chemical Society·Jérôme HannedoucheMartin Wills
May 19, 2005·Journal of the American Chemical Society·Aidan M HayesMartin Wills
Feb 1, 2006·Organic & Biomolecular Chemistry·Takao IkariyaRyoji Noyori
Mar 1, 2006·Chemical Society Reviews·Serafino Gladiali, Elisabetta Alberico
Oct 27, 2007·Accounts of Chemical Research·Takao Ikariya, A John Blacker
Mar 19, 2008·Angewandte Chemie·Theo ZweifelHansjörg Grützmacher
Aug 30, 2008·Chemistry, an Asian Journal·Chao WangJianliang Xiao
Aug 30, 2011·Journal of the American Chemical Society·Taichiro TougeTakao Ikariya
Mar 28, 2012·Journal of the American Chemical Society·Jessica F SonnenbergRobert H Morris
Nov 3, 2012·Journal of the American Chemical Society·Jiahong LiJingen Deng
Apr 10, 2013·Journal of the American Chemical Society·Stephen K Murphy, Vy M Dong
Apr 23, 2013·Chemistry : a European Journal·Agnieszka BartoszewiczBelén Martín-Matute
Aug 21, 2013·The Journal of Organic Chemistry·Zhijia Fang, Martin Wills
Dec 2, 2014·Journal of the American Chemical Society·Xiao-Hui YangQi-Lin Zhou

❮ Previous
Next ❯

Citations

Feb 26, 2016·Chemical Communications : Chem Comm·Cheng TianEric Meggers
Mar 25, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Raffaele MolinariTeresa Poerio
Aug 31, 2016·Topics in Current Chemistry·Bogdan Štefane, Franc Požgan
Jun 11, 2015·Chemical Reviews·Dong Wang, Didier Astruc
Apr 19, 2016·Organic & Biomolecular Chemistry·Sonia De AngelisRenzo Luisi
Aug 12, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Nahury Castellanos-BlancoJuventino J García
Dec 7, 2018·Angewandte Chemie·Ronald A Farrar-TobarJohannes G de Vries
Dec 29, 2017·Chemistry : a European Journal·Ronald A Farrar-TobarJohannes G de Vries

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.