Efficient C(sp³)-H bond functionalization of isochroman by AZADOL catalysis

Organic Letters
Wataru Muramatsu, Kimihiro Nakano

Abstract

A novel organocatalytic C(sp(3))-H bond functionalization of isochroman under practical conditions has been developed. In the presence of 5.0 mol % of AZADOL, the catalysis proceeded successfully with a broad range of substrates and nucleophiles in excellent yields.

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Citations

Jan 16, 2016·The Journal of Organic Chemistry·Huw M L Davies, Daniel Morton
Dec 18, 2015·The Journal of Physical Chemistry. a·Igor B KrylovAlexander Olegovich Terent'ev
Dec 22, 2015·Chemical Communications : Chem Comm·Ryu SakamotoKeiji Maruoka
May 22, 2018·Organic & Biomolecular Chemistry·Longyang DianYunfei Du
May 23, 2019·Organic & Biomolecular Chemistry·Mustafa Uygur, Olga García Mancheño
Sep 12, 2018·Beilstein Journal of Organic Chemistry·Igor B KrylovAlexander O Terent'ev

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