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Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing

BMC Genomics

Sep 19, 2012

José A RoblesJennifer M Taylor

Abstract

RNA sequencing (RNA-Seq) has emerged as a powerful approach for the detection of differential gene expression with both high-throughput and high resolution capabilities possible depending upon the experimental design chosen. Multiplex experimental designs are now readily available, thes...read more

Mentioned in this Paper

Tissue-Specific Gene Expression
Sequencing
MRNA Differential Display
Sequence Determinations, RNA
20
2
499
Paper Details
References
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  • Citations67
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  • References42
  • Citations67
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Efficient experimental design and analysis strategies for the detection of differential expression using RNA-Sequencing

BMC Genomics

Sep 19, 2012

José A RoblesJennifer M Taylor

PMID: 22985019

DOI: 10.1186/1471-2164-13-484

Abstract

RNA sequencing (RNA-Seq) has emerged as a powerful approach for the detection of differential gene expression with both high-throughput and high resolution capabilities possible depending upon the experimental design chosen. Multiplex experimental designs are now readily available, thes...read more

Mentioned in this Paper

Tissue-Specific Gene Expression
Sequencing
MRNA Differential Display
Sequence Determinations, RNA
20
2
499

Similar Papers Found In These Feeds

Perturb-seq

Perturb-seq has combined CRISPR gene inactivation and single-cell rna-sequencing (scRNA-seq) and is the newest addition to the geneticist's arsenal, providing scientists with study methods for functional genomics. Discover the latest research here.

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BMC Bioinformatics

A comparison of methods for differential expression analysis of RNA-seq data

BMC BioinformaticsMarch 19, 2013
Charlotte Soneson, Mauro Delorenzi
Paper Details
References
  • References42
  • Citations67
12345
  • References42
  • Citations67
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