Efficient generation of highly functionalized fused oxazepine frameworks based on a CAN-catalyzed four-component tetrahydropyridine synthesis/ring-closing metathesis sequence

The Journal of Organic Chemistry
Vellaisamy SridharanJ Carlos Menéndez

Abstract

1-Allyl(propargyl)-6-allyl(propargyl)oxy-1,4,5,6-tetrahydropyridines, obtained through a CAN-catalyzed four-component reaction, were transformed into highly functionalized pyrido[2,1-b][1,3]oxazepines by ring-closing metathesis (RCM) and ring-closing enyne metathesis (RCEYM) processes, which constitute the first examples of the preparation of 1,3-oxazepine systems using metathesis reactions.

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Citations

Dec 12, 1991·Biochimica Et Biophysica Acta·K Sigler, M Höfer
Aug 13, 2011·Chemical Reviews·Vellaisamy SridharanJ Carlos Menéndez
Jan 23, 2019·Chemical Communications : Chem Comm·Kai GaoHanfeng Ding
Jul 2, 2010·Chemical Society Reviews·Steven P Nolan, Hervé Clavier
Nov 2, 2019·Organic & Biomolecular Chemistry·Mahanandaiah KurvaLaurent El Kaim
Apr 3, 2010·Chemical Reviews·Vellaisamy Sridharan, J Carlos Menéndez
Feb 21, 2019·The Journal of Organic Chemistry·Deok Kyun AhnSang Kook Woo
Oct 7, 2010·Journal of Combinatorial Chemistry·Roland E DolleWei Zhang

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