Efficient injection of low-mass ions into high magnetic field Fourier transform ion cyclotron resonance mass spectrometers

Rapid Communications in Mass Spectrometry : RCM
Behrooz ZekavatTouradj Solouki

Abstract

Low-mass cut-off restrictions for injecting ions from external ion sources into high magnetic fields impose limitations for wide mass range analyses with Fourier transform ion cyclotron resonance (FTICR) instruments. Radio-frequency (RF)-only quadrupole ion guides (QIGs) with higher frequencies can be used to overcome low-mass cut-off in FTICR instruments. RF signals (1.0 MHz to 10.0 MHz) were applied to QIGs to transfer externally generated ions from either electron ionization (EI) or electrospray ionization (ESI) sources into ICR cells of 9.4 T FTICR mass spectrometers. Efficiencies of QIGs were evaluated using externally generated ions from: EI of acetone, air, and perfluorotributylamine mixture, EI of gas chromatography (GC)-separated components of a standard sample mixture, and ESI of complex mixtures such as petroleum and fulvic acid samples. We were able to transfer ions with m/z as low as 26 from an external EI source into the ICR cell of a 9.4 T FTICR mass spectrometer and extend the operational low-mass range for ESI-FTICR analyses. High mass resolving power and mass measurement accuracy of GC/FTICR mass spectrometry were utilized to discriminate between oxygenated and non-oxygenated compounds in a 'Grob' sample. Ion ...Continue Reading

References

Oct 13, 1998·Mass Spectrometry Reviews·A G MarshallG S Jackson
Nov 22, 2002·Journal of the American Society for Mass Spectrometry·Bruce E WilcoxAlan G Marshall
Dec 18, 2002·Journal of the American Society for Mass Spectrometry·Peter B O'ConnorWilliam E Earle
Dec 15, 2005·Rapid Communications in Mass Spectrometry : RCM·Peter B O'connorCheng Zhao
Dec 17, 2009·Journal of the American Society for Mass Spectrometry·Alireza FattahiTouradj Solouki
Apr 8, 2011·Journal of the American Society for Mass Spectrometry·Steven C BeuAlan G Marshall
Feb 1, 2013·Angewandte Chemie·Behrooz Zekavat, Touradj Solouki
Jan 1, 1996·Journal of the American Society for Mass Spectrometry·S Guan, A G Marshall
Oct 1, 1995·Journal of the American Society for Mass Spectrometry·J A MartoP A Limbach

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Citations

Jan 13, 2016·Journal of Mass Spectrometry : JMS·Abayomi D OlaitanTouradj Solouki
Aug 21, 2015·Journal of the American Society for Mass Spectrometry·Mahsan MiladiTouradj Solouki

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