Efficient voxel navigation for proton therapy dose calculation in TOPAS and Geant4.

Physics in Medicine and Biology
J SchümannJ Perl

Abstract

A key task within all Monte Carlo particle transport codes is 'navigation', the calculation to determine at each particle step what volume the particle may be leaving and what volume the particle may be entering. Navigation should be optimized to the specific geometry at hand. For patient dose calculation, this geometry generally involves voxelized computed tomography (CT) data. We investigated the efficiency of navigation algorithms on currently available voxel geometry parameterizations in the Monte Carlo simulation package Geant4: G4VPVParameterisation, G4VNestedParameterisation and G4PhantomParameterisation, the last with and without boundary skipping, a method where neighboring voxels with the same Hounsfield unit are combined into one larger voxel. A fourth parameterization approach (MGHParameterization), developed in-house before the latter two parameterizations became available in Geant4, was also included in this study. All simulations were performed using TOPAS, a tool for particle simulations layered on top of Geant4. Runtime comparisons were made on three distinct patient CT data sets: a head and neck, a liver and a prostate patient. We included an additional version of these three patients where all voxels, includi...Continue Reading

References

Aug 15, 2008·Physics in Medicine and Biology·Harald PaganettiMartijn Engelsman

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Citations

May 31, 2015·International Journal of Radiation Oncology, Biology, Physics·Jan SchuemannHarald Paganetti
Jan 22, 2017·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·V GiacomettiR W Schulte
Nov 26, 2015·Technology in Cancer Research & Treatment·Joost Mathijs VerburgHarald Paganetti
Sep 6, 2018·Physics in Medicine and Biology·Yizheng ChenHarald Paganetti
Feb 27, 2015·Physics in Medicine and Biology·Drosoula GiantsoudiHarald Paganetti
May 14, 2020·Radiation Research·Hongyu ZhuJan Schuemann
Jul 16, 2020·The British Journal of Radiology·Wei Yang Calvin KohJames Cheow Lei Lee
Jun 11, 2015·Physics in Medicine and Biology·J Ramos MéndezB Faddegon
Apr 2, 2016·Physics in Medicine and Biology·Julien BertDimitris Visvikis
Dec 31, 2014·Physics in Medicine and Biology·C GrassbergerH Paganetti
Nov 22, 2014·Physics in Medicine and Biology·S MarcatiliM Bardiès
Mar 24, 2016·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Yeon Soo YeomBeom Sun Chung
Jul 6, 2014·Physics in Medicine and Biology·J SchuemannH Paganetti
Sep 27, 2014·Physics in Medicine and Biology·Hsin-Hon LinMeei-Ling Jan
Sep 21, 2016·Physics in Medicine and Biology·Yeon Soo YeomChoonsik Lee
Jun 11, 2015·Physics in Medicine and Biology·J Ramos-MéndezB Faddegon
Mar 2, 2021·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Bangho ShinBeom Sun Chung

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