Egg-laying and brooding stage-specific hormonal response and transcriptional regulation in pituitary of Muscovy duck (Cairina moschata)

Poultry Science
Pengfei YeZhaoyu Geng

Abstract

Broodiness is an interesting topic in reproductive biology for its reduced egg production. The strong brooding trait of Muscovy duck has become a major factor restricting the development of its industry. Broody phenotype and environmental factors influencing broodiness in poultry have been extensively studied, but the molecular regulation mechanism of broodiness remains unclear. In this research, the Muscovy duck reproductive endocrine hormones and pituitary transcriptome profiles during egg-laying phases (LP) and brooding phases (BP) were studied. During BP (n = 19), prolactin (PRL) levels was higher, while progesterone (P4) and estradiol (E2) were lower as compared to ducks during their LP (n = 20) (P < 0.01). We then examined the pituitary transcriptome of Muscovy duck at the 2 reproductive stages. A total of 398 differentially expressed genes included 20 transcription factors were identified (fold change ≥ 1.5, P < 0.01). There were 109 upregulated and 289 downregulated genes at brooding phases (n = 6) compared with egg-laying phases (n = 6). Real-time quantitative PCR analysis was carried out to verify the transcriptome results. The present study suggested that neuroactive ligand-receptor interaction pathway, calcium signa...Continue Reading

References

Dec 1, 1984·The Journal of Experimental Zoology·P J SharpT R Hall
Oct 24, 2000·Molecular Endocrinology·F GayG Salbert
Mar 20, 2003·Molecular and Cellular Endocrinology·Guadalupe Maya-Núñez, P Michael Conn
Aug 14, 2003·Biochimica Et Biophysica Acta·Thomas F J Martin
Mar 18, 2006·Molecular Endocrinology·Michael A CharlesDavid F Gordon
Jun 24, 2006·European Journal of Endocrinology·Angelika GutenbergMichael Buchfelder
Jun 3, 2008·Nature Methods·Ali MortazaviBarbara Wold
Aug 16, 2008·Genomics·Olena Morozova, Marco A Marra
Jun 6, 2009·Bioinformatics·Ruiqiang LiJun Wang
Aug 27, 2009·Nature Reviews. Endocrinology·Suzy D C Bianco, Ursula B Kaiser
Aug 28, 2010·Molecular and Cellular Endocrinology·Weiming ZhengLisa M Halvorson
Nov 11, 2010·Pharmacogenetics and Genomics·Caroline F ThornRuss B Altman
Jan 11, 2013·Physiological Reviews·R A D BathgateR J Summers
Nov 20, 2013·Frontiers in Neuroendocrinology·Robert J Handa, Michael J Weiser
Dec 21, 2013·Neuroendocrinology·P GrachevK T O'Byrne
Jan 29, 2014·Molecular Biology Reports·Fang ChenChunMei Li
Apr 26, 2014·The Journal of Clinical Investigation·Stephanie SisleyRandy J Seeley
May 23, 2015·Molecular Cell·Jason A ReuterMichael P Snyder
Aug 15, 2015·BMC Pregnancy and Childbirth·Eva ThorellPer Kristiansson
May 22, 2017·Current Topics in Developmental Biology·Xiong YangKe Tang
Dec 28, 2018·International Journal of Molecular Sciences·Xiangfeng QinGuangfu Hu

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