Eicosanoids, fatty acids and neutrophils: their relevance to the pathophysiology of disease

Prostaglandins, Leukotrienes, and Essential Fatty Acids
E J Bates

Abstract

PUFA and their eicosanoid metabolites are potent biological modifiers. They have beneficial effects in a number of diseases, which may result in part from their direct actions on neutrophils as well as from their ability to modulate eicosanoid biosynthesis. A consideration of their interactions with other cell types, e.g. lymphocytes and macrophages, is beyond the scope of this review. Small alterations in structure can result in large changes in the neutrophil response. This will have important implications for the further development and use of fatty acids for therapeutic purposes.

References

May 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·P Borgeat, B Samuelsson
Sep 1, 1978·The Journal of Experimental Medicine·I M GoldsteinG Weissmann
Feb 1, 1992·The American Journal of Clinical Nutrition·L G ClelandR A Gibson
May 1, 1992·Medical Hypotheses·U N DasM Padma
Jul 1, 1992·American Journal of Respiratory Cell and Molecular Biology·T B CasaleE J Carolan
Aug 1, 1992·Clinical and Experimental Immunology·R H Lawrence, T C Sorrelli
Sep 1, 1992·British Journal of Pharmacology·P P McDonaldP Borgeat
Jan 1, 1992·Progress in Lipid Research·D F Horrobin
Jan 1, 1992·Archives of Dermatological Research·L Michel, L Dubertret
Nov 1, 1992·Clinical and Experimental Immunology·J E Palmblad, R Lerner
Nov 1, 1992·The American Review of Respiratory Disease·S J Feinmark
Sep 1, 1992·The Journal of Investigative Dermatology·O WiedowE Christophers
Jan 1, 1992·Journal of Inherited Metabolic Disease·H W MoserW Krivit
May 1, 1992·Infection and Immunity·T C SorrellK Sztelma
Jan 1, 1992·British Medical Bulletin·A B Kay, C J Corrigan
Jul 15, 1992·Biochemical and Biophysical Research Communications·F J RollC N Serhan
Jun 1, 1991·The Journal of Clinical Investigation·H A LehrK Messmer
Jan 1, 1991·Agents and Actions·P ContiM Bongrazio
Apr 1, 1991·Prostaglandins, Leukotrienes, and Essential Fatty Acids·H HughesA A Taylor
Sep 1, 1991·The American Review of Respiratory Disease·J C FarmerR O Webster
Nov 14, 1991·Biochemical and Biophysical Research Communications·T H LeeB W Spur
Oct 1, 1991·Journal of Applied Physiology·S RosengrenK E Arfors
Feb 1, 1992·The Journal of Investigative Dermatology·J M SchröderE Christophers
Jan 1, 1991·Advances in Experimental Medicine and Biology·S FioreC N Serhan
Jan 1, 1991·International Archives of Allergy and Applied Immunology·J Dry, D Vincent
Jan 1, 1991·The Journal of Allergy and Clinical Immunology·M CarlsonP Venge

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Citations

Jul 27, 1999·Lipids·A SellmayerP C Weber
Jan 1, 1997·Free Radical Biology & Medicine·G HotterJ Roselló-Catafau
Apr 16, 2002·European Journal of Clinical Investigation·G J A WantenA H J Naber
Apr 29, 1998·Annual Review of Physiology·V L Schuster
Dec 9, 1997·Anesthesia and Analgesia·N NathanP Feiss
May 23, 2007·The Veterinary Journal·Joseph A Impellizeri, D Glen Esplin
Jul 8, 2007·Cognitive Science·Ping LiBrian Mac Whinney
Jul 22, 2016·International Journal of Molecular Sciences·Wen-Bin XueZhi-Gang Zhou
Dec 11, 2019·Nutrients·Urszula RadzikowskaMilena Sokolowska
Sep 14, 1999·The American Journal of Physiology·M L PucciV L Schuster
Jun 28, 2021·Toxicological Sciences : an Official Journal of the Society of Toxicology·Michael J YaegerKymberly M Gowdy

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