Eicosapentaenoic acid in cancer improves body composition and modulates metabolism

Nutrition
Giulia PappalardoPaula Ravasco

Abstract

The objective of this review article is to present the most recent intervention studies with EPA on nutritional outcomes in cancer patients, e.g. nutritional status, weight & lean body mass. For this purpose a PubMed(®) and MedLine(®) search of the published literature up to and including January 2014 that contained the keywords: cancer, sarcopenia, EPA, ω-3 fatty acids, weight, intervention trial, muscle mass was conducted. The collected data was summarized and written in text format and in tables that contained: study design, patient' population, sample size, statistical significance and results of the intervention. The paper will cover malignancy, body composition, intervention with EPA, physiological mechanisms of action of EPA, effect of EPA on weight and body composition, future research. In cancer patients deterioration of muscle mass can be present regardless of body weight or Body Mass Index (BMI). Thus, sarcopenia in cancer patients with excessive fat mass (FM), entitled sarcopenic obesity, has gained greater relevance in clinical practice; it can negatively influence patients' functional status, tolerance to treatments & disease prognosis. The search for an effective nutritional intervention that improves body compos...Continue Reading

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Citations

Nov 18, 2015·Journal of Hepato-biliary-pancreatic Sciences·Atsushi KobayashiShinji Uemoto
Oct 28, 2015·Mediators of Inflammation·Alessio MolfinoAlessandro Laviano
Jul 4, 2016·Current Gastroenterology Reports·Matthew R KappusStephen A McClave
Oct 27, 2016·Current Opinion in Supportive and Palliative Care·Alessandro LavianoAngela Koverech
Apr 5, 2017·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·T R ChagasE A Nunes
Sep 16, 2017·European Journal of Preventive Cardiology·Louise G Shewan
Jan 10, 2020·Journal of Cachexia, Sarcopenia and Muscle·Carla M PradoAlessandro Laviano
Aug 24, 2017·Current Opinion in Clinical Nutrition and Metabolic Care·Matthew S BrookPhilip J Atherton
Sep 7, 2018·European Journal of Clinical Nutrition·Vickie E Baracos
Aug 17, 2019·Journal of Clinical Medicine·Paula Ravasco
Nov 23, 2016·The Journal of Physiological Sciences : JPS·King-Chuen WuYuk-Man Leung
May 1, 2019·Nutrients·Raquel D S Freitas, Maria M Campos
May 23, 2017·Therapeutic Advances in Medical Oncology·Zaira AversaMaurizio Muscaritoli
Sep 9, 2017·Current Oncology Reports·Rishi Jain, Efrat Dotan
May 1, 2018·The Proceedings of the Nutrition Society·Dalton L Schiessel, Vickie E Baracos
Feb 18, 2016·Nutrition and Metabolic Insights·Amritpal S BhullarVera C Mazurak
Dec 2, 2020·Cells·Giorgio AquilaRosanna Piccirillo
Feb 4, 2021·Comprehensive Reviews in Food Science and Food Safety·Yandan WangXingguo Wang
Feb 20, 2021·Cancer Treatment and Research Communications·Timotius Ivan Hariyanto, Andree Kurniawan
Dec 7, 2018·Pharmacology & Therapeutics·Marc HilmiFrançois Goldwasser
Jun 11, 2021·Signal Transduction and Targeted Therapy·Fanglong WuHongmei Zhou
Jul 16, 2021·Frontiers in Pharmacology·Jong Min ParkKi Baik Hahm
Aug 15, 2021·Nutrition Reviews·Jenny G TurcottOscar Arrieta

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