Eight years experience in treatment of prosthetic joint infections at a teaching hospital in Central Taiwan

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
Shu-Wen TsengJen-Hsian Wang

Abstract

Prosthetic joint infection (PJI) has become an important issue in the management of patients who receive prostheses. We compared the clinical outcomes of PJIs caused by Gram-negative bacteria (GN PJIs) and Gram-positive bacteria (GP PJIs). Patients with culture-proven PJIs admitted to China Medical University Hospital between March 2001 and March 2009 were included in this retrospective study. Fifty-nine patients were diagnosed with PJI during the study period. Nineteen patients had GN PJIs (mean age: 68 years) and 40 had GP PJIs (mean age: 61 years). The most common comorbid condition was diabetes mellitus (23.7%) and the most common presentation was joint pain (79.7%). Staphylococcus aureus was the most common pathogen, whereas Klebsiella pneumoniae was the most common Gram-negative pathogen. The GN PJI group included more cases of hematogenous infection (36.8% vs. 20%; p < 0.001), showed a shorter interval between onset of infection symptoms and surgical intervention (median: 8 days vs. 21 days; p = 0.04), and required longer medical treatment (median: 259 days vs. 161 days; p = 0.04). In comparison with patients whose prostheses were eventually removed, patients whose prostheses were not removed had a shorter interval betwe...Continue Reading

References

Jan 1, 1988·The Journal of Arthroplasty·J A GouletE M Salvati
Nov 1, 1985·Reviews of Infectious Diseases·H C Neu
Jul 1, 1984·The American Journal of Medicine·R D InmanC L Christian
Aug 1, 1997·Annals of the Rheumatic Diseases·C J KaandorpB A Dijkmans
Sep 7, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P TattevinC Carbon
Mar 26, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A M MeehanM R Keating
Sep 10, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G L PavoniM Venditti
Mar 25, 2005·Acta Orthopaedica·Daniëlle NeutHenk J Busscher
Jan 20, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C E MarculescuD R Osmon
Apr 29, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R R LafferW Zimmerli
Jun 27, 2006·The Journal of Bone and Joint Surgery. British Volume·J E PhillipsR J Grimer
Sep 12, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L LegoutY Mouton
Apr 4, 2007·The Journal of Bone and Joint Surgery. American Volume·Steven KurtzMichael Halpern
Aug 3, 2007·The Journal of Bone and Joint Surgery. American Volume·Michael H HuoJavad Parvizi
Jun 7, 2008·The Journal of Arthroplasty·Steven M KurtzJavad Parvizi
Aug 9, 2008·Current Infectious Disease Reports·Andrej Trampuz, Werner Zimmerli
Jan 6, 2009·The Journal of Bone and Joint Surgery. American Volume·Esa JämsenTeemu Moilanen
Jun 6, 2009·The Journal of Arthroplasty·Kevin L OngJavad Parvizi
Aug 21, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Pang-Hsin HsiehSteve W Ueng
Aug 3, 2010·The Journal of Bone and Joint Surgery. British Volume·C A Willis-OwenD K Martin

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Citations

May 8, 2013·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Chien-Ming ChaoPo-Ren Hsueh
May 13, 2014·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jorgelina de SanctisSteven Schmitt
Jun 13, 2015·Journal of Patient Safety·Margaret KuderJonathan M Zenilman
Apr 4, 2014·Clinical Microbiology Reviews·Aaron J Tande, Robin Patel
Apr 24, 2019·Journal of Bone and Joint Infection·Noam ShohatJavad Parvizi
Mar 19, 2019·Indian Journal of Medical Microbiology·Sujeesh SebastianBenu Dhawan

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