Eighteen years of paediatric extracorporeal membrane oxygenation and ventricular assist devices: insight regarding late outcomes

Cardiology in the Young
Shawn M ShahJeffrey P Jacobs

Abstract

We reviewed all patients who were supported with extracorporeal membrane oxygenation and/or ventricular assist device at our institution in order to describe diagnostic characteristics and assess mortality. A retrospective cohort study was performed including all patients supported with extracorporeal membrane oxygenation and/or ventricular assist device from our first case (8 October, 1998) through 25 July, 2016. The primary outcome of interest was mortality, which was modelled by the Kaplan-Meier method. A total of 223 patients underwent 241 extracorporeal membrane oxygenation runs. Median support time was 4.0 days, ranging from 0.04 to 55.8 days, with a mean of 6.4±7.0 days. Mean (±SD) age at initiation was 727.4 days (±146.9 days). Indications for extracorporeal membrane oxygenation were stratified by primary indication: cardiac extracorporeal membrane oxygenation (n=175; 72.6%) or respiratory extracorporeal membrane oxygenation (n=66; 27.4%). The most frequent diagnosis for cardiac extracorporeal membrane oxygenation patients was hypoplastic left heart syndrome or hypoplastic left heart syndrome-related malformation (n=55 patients with HLHS who underwent 64 extracorporeal membrane oxygenation runs). For respiratory extraco...Continue Reading

References

Oct 4, 2000·The Annals of Thoracic Surgery·J P JacobsR P Burke
Apr 1, 2010·World Journal for Pediatric & Congenital Heart Surgery·Kenneth G ShannDonald S Likosky
Nov 20, 2013·The Journal of Thoracic and Cardiovascular Surgery·Christopher E MascioSara K Pasquali
Dec 26, 2013·The Korean Journal of Thoracic and Cardiovascular Surgery·Ivan WilmotDavid Morales
Sep 2, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Robert J Boucek JrAnn Steele
Feb 14, 2016·The Annals of Thoracic Surgery·Daizo TanakaJohn W C Entwistle
Feb 6, 2017·Cardiology in the Young·Alfred Asante-Korang, Jeffrey P Jacobs

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Citations

Apr 23, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jeffrey P JacobsMarvin J Slepian

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