EIT based pulsatile impedance monitoring during spontaneous breathing in cystic fibrosis

Physiological Measurement
Sabine Krueger-ZiolekKnut Moeller

Abstract

Evaluating the lung function in patients with obstructive lung disease by electrical impedance tomography (EIT) usually requires breathing maneuvers containing deep inspirations and forced expirations. Since these maneuvers strongly depend on the patient's co-operation and health status, normal tidal breathing was investigated in an attempt to develop continuous maneuver-free measurements. Ventilation related and pulsatile impedance changes were systematically analyzed during normal tidal breathing in 12 cystic fibrosis (CF) patients and 12 lung-healthy controls (HL). Tidal breaths were subdivided into three inspiratory (In1, In2, In3) and three expiratory (Ex1, Ex2, Ex3) sections of the same amplitude of global impedance change. Maximal changes of the ventilation and the pulsatile impedance signal occurring during these sections were determined (▵I V and ▵I P). Differences in ▵I V and ▵I P among sections were ascertained in relation to the first inspiratory section. In addition, ▵I V/▵I P was calculated for each section. Medians of changes in ▵I V were  <0.05% in all sections for both subject groups. Both groups showed a similar pattern of ▵I P changes during tidal breathing. Changes in ▵I P first decreased during inspiration ...Continue Reading

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Citations

May 5, 2018·Physiological Measurement·Jennifer L MuellerEmily DeBoer
Jan 28, 2020·Annual Reviews in Control·Thiago de Castro MartinsMarcos de Sales Guerra Tsuzuki

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