Elastic materials for tissue engineering applications: Natural, synthetic, and hybrid polymers

Acta Biomaterialia
Anna M J CoenenSamaneh Ghazanfari

Abstract

Elastin and collagen are the two main components of elastic tissues and provide the tissue with elasticity and mechanical strength, respectively. Whereas collagen is adequately produced in vitro, production of elastin in tissue-engineered constructs is often inadequate when engineering elastic tissues. Therefore, elasticity has to be artificially introduced into tissue-engineered scaffolds. The elasticity of scaffold materials can be attributed to either natural sources, when native elastin or recombinant techniques are used to provide natural polymers, or synthetic sources, when polymers are synthesized. While synthetic elastomers often lack the biocompatibility needed for tissue engineering applications, the production of natural materials in adequate amounts or with proper mechanical strength remains a challenge. However, combining natural and synthetic materials to create hybrid components could overcome these issues. This review explains the synthesis, mechanical properties, and structure of native elastin as well as the theories on how this extracellular matrix component provides elasticity in vivo. Furthermore, current methods, ranging from proteins and synthetic polymers to hybrid structures that are being investigated ...Continue Reading

Citations

Sep 22, 2018·Angewandte Chemie·Marijana ĐakovićIvan Kodrin
Jan 27, 2019·Journal of Biomedical Materials Research. Part a·Samaneh GhazanfariAli Khademhosseini
Mar 27, 2019·Tissue Engineering. Part C, Methods·Mollie M SmoakAntonios G Mikos
Apr 16, 2020·Antibiotics·Catarina S MirandaHelena P Felgueiras
Apr 29, 2020·Annual Review of Biomedical Engineering·Anastasia K VarankoAshutosh Chilkoti
Apr 13, 2019·International Journal of Molecular Sciences·Tariq O AbbasCristian P Pennisi
Jun 20, 2019·Frontiers in Bioengineering and Biotechnology·David F Williams
Feb 9, 2021·Bioactive Materials·Keshav Narayan AlagarsamySanjiv Dhingra
Feb 14, 2021·International Journal of Molecular Sciences·Elham PishavarSeeram Ramakrishna
Mar 4, 2020·Carbohydrate Polymers·Henna CassimjeeViness Pillay
Mar 3, 2021·Acta Biomaterialia·Suzette T LustEileen Gentleman
Mar 9, 2021·Bio-medical Materials and Engineering·Kaveh SanaeiNasim Nosoudi
May 6, 2021·Macromolecular Bioscience·Matin RostamitabarSamaneh Ghazanfari
Jun 2, 2021·Chemical Society Reviews·Maksim RodinDirk Kuckling
Jun 8, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Du XiangYanfeng Wang
Jul 30, 2021·Acta Biomaterialia·Patrick M WilliamsonAra Nazarian
Jul 24, 2021·Chemistry of Materials : a Publication of the American Chemical Society·João B CostaSang Jin Lee
Jan 25, 2020·ACS Applied Materials & Interfaces·Olena IvashchenkoStefan Jurga
Nov 10, 2021·Biomacromolecules·Michèle DaiSébastien Lecommandoux

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.