Elastohydrodynamic Synchronization of Adjacent Beating Flagella

Physical Review Fluids
Raymond E GoldsteinMichael R E Proctor

Abstract

It is now well established that nearby beating pairs of eukaryotic flagella or cilia typically synchronize in phase. A substantial body of evidence supports the hypothesis that hydrodynamic coupling between the active filaments, combined with waveform compliance, provides a robust mechanism for synchrony. This elastohydrodynamic mechanism has been incorporated into 'bead-spring' models in which the beating flagella are represented by microspheres tethered by radial springs as they are driven about orbits by internal forces. While these low-dimensional models reproduce the phenomenon of synchrony, their parameters are not readily relatable to those of the filaments they represent. More realistic models which reflect the underlying elasticity of the axonemes and the active force generation, take the form of fourth-order nonlinear PDEs. While computational studies have shown the occurrence of synchrony, the effects of hydrodynamic coupling between nearby filaments governed by such continuum models have been theoretically examined only in the regime of interflagellar distances d large compared to flagellar length L. Yet, in many biological situations d/L ≪ 1. Here, we first present an asymptotic analysis of the hydrodynamic couplin...Continue Reading

References

Jul 12, 2002·Cell Motility and the Cytoskeleton·Charles B Lindemann
Dec 13, 2003·Proceedings of the National Academy of Sciences of the United States of America·MunJu KimThomas R Powers
Feb 21, 2006·Physical Review Letters·Andrej Vilfan, Frank Jülicher
Dec 26, 2006·Biophysical Journal·Boris Guirao, Jean-François Joanny
Feb 1, 2008·Bulletin of Mathematical Biology·Xingzhou YangLisa J Fauci
Jan 1, 2007·Computers & Structures·Sorin M Mitran
Jun 13, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Andreas HilfingerFrank Jülicher
Nov 13, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·J BurkeE Knobloch
Feb 2, 2013·Physical Review Letters·Douglas R BrumleyRaymond E Goldstein
Jul 31, 2014·ELife·Douglas R BrumleyRaymond E Goldstein
Dec 20, 2014·Physical Review Letters·Kirsty Y Wan, Raymond E Goldstein
Apr 4, 2015·Journal of the Royal Society, Interface·P V Bayly, K S Wilson
Jun 5, 2015·Journal of the Royal Society, Interface·Douglas R BrumleyRaymond E Goldstein
Nov 26, 2015·Annual Review of Fluid Mechanics·Raymond E Goldstein

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Citations

Mar 21, 2019·Journal of the Royal Society, Interface·Hermes Gadêlha, Eamonn A Gaffney
Dec 31, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Yi ManEva Kanso
Mar 20, 2018·Physical Review. E·Yoji Kawamura, Remi Tsubaki
Dec 13, 2016·Physical Review Fluids·Douglas R BrumleyMarco Polin
Jan 11, 2018·Soft Matter·Alan Cheng Hou TsangEva Kanso
May 26, 2018·Physical Review Letters·Heather S DaviesLionel Bureau
Nov 23, 2018·Essays in Biochemistry·Kirsty Y Wan
Dec 7, 2019·Physical Review Letters·Brato Chakrabarti, David Saintillan
Dec 18, 2020·Physical Review. E·Maria Christine L LugoMark Nolan P Confesor
Apr 10, 2021·Physical Review Letters·Jian DengLuca Brandt
May 20, 2021·Physical Review. E·Weida Liao, Eric Lauga
Aug 7, 2021·Frontiers in Cell and Developmental Biology·Eamonn A GaffneyBenjamin J Walker

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