Elderly patients had more severe postoperative complications after pancreatic resection: A retrospective analysis of 727 patients

World Journal of Gastroenterology : WJG
Ying-Tai ChenYan-Tao Tian

Abstract

To examine the impact of aging on the short-term outcomes following pancreatic resection (PR) in elderly patients. A retrospective cohort study using prospectively collected data was conducted at the China National Cancer Center. Consecutive patients who underwent PR from January 2004 to December 2015 were identified and included. 'Elderly patient' was defined as ones age 65 and above. Comorbidities, clinicopathology, perioperative variables, and postoperative morbidity and mortality were compared between the elderly and young patients. Univariate and multivariate analyses were performed using the Cox proportional hazard model for severe postoperative complications (grades IIIb-V). A total of 454 (63.4%) patients were < 65-years-old and 273 (36.6%) patients were ≥ 65-years-old, respectively. Compared to patients < 65-years-old, elderly patients had worse American Society of Anesthesiologists scores (P = 0.007) and more comorbidities (62.6% vs 32.4%, P < 0.001). Elderly patients had more severe postoperative complications (16.8% vs 9.0%, P = 0.002) and higher postoperative mortality rates (5.5% vs 0.9%, P < 0.001). In the multivariate Cox proportional hazards model for severe postoperative complications, age ≥ 65 years [hazard r...Continue Reading

References

Jun 28, 2007·Yonsei Medical Journal·Chang Moo KangByong Ro Kim
Sep 12, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Roberto BallarinGiorgio Enrico Gerunda
Jul 30, 2009·Annals of Surgery·Pierre A ClavienMasatoshi Makuuchi
Oct 21, 2009·Archives of Surgery·Wande B PrattCharles M Vollmer
Aug 18, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Saboor KhanMichael B Farnell
Sep 9, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Minna K LeeJohn D Allendorf
Jan 29, 2011·World Journal of Surgical Oncology·Guy LahatJosef M Klausner
Jul 13, 2011·Pancreas·Valeria de FrancoNicolas Regenet
Sep 1, 2011·Annals of Surgical Oncology·Carsten KamphuesMarcus Bahra
Sep 13, 2011·World Journal of Surgical Oncology·Yasuhiro ItoYuko Kitagawa
Apr 25, 2012·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·A W C KowK H Liau
Aug 14, 2012·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Marcovalerio MelisElliot Newman
Sep 8, 2012·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Prashant SukharamwalaPeter DeVito
Sep 25, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·O TurriniUNKNOWN French Surgical Association (AFC)
Oct 30, 2012·Surgery Today·Shuji SuzukiMamoru Suzuki
Dec 12, 2012·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Melissa Oliveira-CunhaAndrew Malvern Smith
Mar 29, 2014·Langenbeck's Archives of Surgery·M AdhamP J Valette
Jan 4, 2015·Journal of Geriatric Oncology·Jessica M FrakesRavi Shridhar
May 7, 2015·Cirugía española·Francisco SchlottmannLucas McCormack
Apr 12, 2016·Annals of Gastroenterology : Quarterly Publication of the Hellenic Society of Gastroenterology·Daniel AnsariRoland Andersson
Aug 9, 2016·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Ayman El NakeebMohamed Abdel Wahab
Nov 8, 2016·Current Opinion in Ophthalmology·Hideki Fukuoka, Natalie A Afshari

❮ Previous
Next ❯

Citations

Jul 18, 2019·Surgical Endoscopy·Yun LiangWei Wang
Apr 24, 2019·Geriatrics·John R OgdenJoleen M Hubbard
Jan 9, 2021·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Yan WangUNKNOWN On behalf the International Surgical Outcomes Study (ISOS) group in China
Feb 27, 2021·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jonathan J HueJeffrey M Hardacre

❮ Previous
Next ❯

Methods Mentioned

BETA
pancreatectomy

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine
Jingyu DengXishan Hao
Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Christopher J GouveiaRobson Capasso
Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Emily Rothbaum PeritoPhilip Rosenthal
© 2022 Meta ULC. All rights reserved