Elderly patients undergoing cystectomy, comparing preoperative American Society of Anesthesiology and Eastern Cooperative Oncology Group scores and operative approaches

Urologia
Christopher MartinEmanuela Trenti

Abstract

To evaluate preoperative scoring systems and operative management and their relation to complications in patients older than 75 years undergoing cystectomy at two academic institutions. In total, 212 patients aged 75-95 years with muscle invasive bladder cancer underwent cystectomy at the University of Utah and Central Hospital of Bolzano, Italy. The rates of Grade 3 Clavien-Dindo complications and above in radical cystectomy patients (n = 199) were compared using Eastern Cooperative Oncology Group Scores and American Society of Anesthesiologists Physical Status Classification. The rates of Grade 3 Clavien-Dindo complications and above were also compared by urinary diversion type. Logistic regression was used to control for source institution. In total, 199 cases were included in the primary analysis. Neither of the preoperative scoring systems were predictive for identification of radical cystectomy patients with ⩾Grade 3 Clavien-Dindo complications. In secondary analysis (n = 212, including partial cystectomy), none of the urinary diversion types associated with radical cystectomy had a significantly different rate of complications. However, partial cystectomy (n = 13) had a significantly lower rate of complications. Complica...Continue Reading

References

Feb 7, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J P SteinD G Skinner
Feb 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephan MadersbacherUrs E Studer
Dec 22, 2004·BMC Cancer·William H HallSrinivasan Vijayakumar
Nov 4, 2006·World Journal of Urology·Jason A EfstathiouWilliam U Shipley
Jun 2, 2009·European Urology·Michael FroehnerUrs E Studer
Jun 30, 2009·European Urology·Casey K NgDouglas S Scherr
Nov 3, 2009·Urologic Oncology·Shahrokh F ShariatMichael J Droller
Nov 17, 2009·BJU International·Shahrokh F ShariatBernard H Bochner
Nov 20, 2009·Cancer·John L GoreUNKNOWN Urologic Diseases in America Project
Dec 19, 2009·Urology·Clemens WehrbergerStephan Madersbacher
Mar 15, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J FerlayF Bray
Aug 3, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·Florian RoghmannJüri Palisaar
Sep 23, 2014·World Journal of Urology·David C JohnsonAngela B Smith
Dec 3, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J SchiffmannP I Karakiewicz
Feb 24, 2016·Urologic Oncology·Meera R ChappidiTrinity J Bivalacqua
Mar 5, 2016·Current Treatment Options in Oncology·Omar M S El-TajiSyed A Hussain

❮ Previous
Next ❯

Citations

Nov 7, 2019·Minerva urologica e nefrologica = The Italian journal of urology and nephrology·Cosimo De NunzioAlessia Brigido

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Australian and New Zealand Journal of Surgery
K KIRKLAND
Actas urologicas españolas
J SarrocaE Zungri
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Amit GuptaElena B Elkin
Current Opinion in Urology
John J Knoedler, Igor Frank
New York State Journal of Medicine
W F WHITMORE, N P BEALL
© 2021 Meta ULC. All rights reserved