Electric and magnetic stimulation of human motor cortex: surface EMG and single motor unit responses

The Journal of Physiology
B L DayP D Thompson

Abstract

1. The effects of different forms of brain stimulation on the discharge pattern of single motor units were examined using the post-stimulus time histogram (PSTH) technique and by recording the compound surface electromyographic (EMG) responses in the first dorsal interosseous (FDI) muscle. Electrical and magnetic methods were used to stimulate the brain through the intact scalp of seven normal subjects. Electrical stimuli were applied either with the anode over the lateral central scalp and the cathode at the vertex (anodal stimulation) or with the anode at the vertex and the cathode lateral (cathodal stimulation). Magnetic stimulation used a 9 cm diameter coil centred at the vertex; current in the coil flowed either clockwise or anticlockwise when viewed from above. 2. Supramotor threshold stimuli produced one or more narrow (less than 2 ms) peaks of increased firing in the PSTH of all thirty-two units studied. Anodal stimulation always produced an early peak. The latencies of the peaks produced by other forms of stimulation, or by high intensities of anodal stimulation, were grouped into four time bands relative to this early peak, at intervals of -0.5 to 0.5, 1-2, 2.5-3.5 and 4-5.5 ms later. Peaks occurring within these inte...Continue Reading

Citations

Jul 10, 2003·Lancet Neurology·Masahito Kobayashi, Alvaro Pascual-Leone
Nov 2, 2004·Experimental Brain Research·F GinanneschiA Rossi
Jun 15, 2014·Neuroscience·O LöfbergJ Karhu
May 20, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Daniel E LumsdenJean-Pierre Lin
Mar 1, 1998·Trends in Cognitive Sciences·V Walsh, A Cowey
Aug 1, 1992·Electroencephalography and Clinical Neurophysiology·T UozumiY Murai
Dec 1, 1991·Electroencephalography and Clinical Neurophysiology·P M RossiniE Ferrari
Jun 1, 1991·Electroencephalography and Clinical Neurophysiology·T C BrittonR Benecke
Sep 1, 1990·Electroencephalography and Clinical Neurophysiology·M InghilleriM Manfredi
Aug 1, 1994·Electroencephalography and Clinical Neurophysiology·F ValzaniaD De Grandis
Jun 1, 1994·Electroencephalography and Clinical Neurophysiology·Y UgawaI Kanazawa
Feb 1, 1994·Electroencephalography and Clinical Neurophysiology·A Pascual-LeoneM Hallett
Dec 1, 1993·Electroencephalography and Clinical Neurophysiology·F Awiszus, H Feistner
Aug 15, 2000·Epilepsy Research·K J WerhahnS Noachtar
Apr 29, 1998·Epilepsy Research·U ZiemannW Paulus
Dec 16, 1998·Electroencephalography and Clinical Neurophysiology·J MathisC W Hess
Sep 19, 1998·Electroencephalography and Clinical Neurophysiology·G W ThickbroomF L Mastaglia
Dec 1, 1995·Electroencephalography and Clinical Neurophysiology·Y TeraoI Kanazawa
Feb 1, 1996·Electroencephalography and Clinical Neurophysiology·M FujikiS Ueno
Nov 18, 1997·Electroencephalography and Clinical Neurophysiology·B HauptmannH Hummelsheim
Aug 1, 1996·Electroencephalography and Clinical Neurophysiology·S IzumiN Chino
Jun 1, 1996·Electroencephalography and Clinical Neurophysiology·S A WilsonF L Mastaglia
Apr 1, 1995·Electroencephalography and Clinical Neurophysiology·P JennumA Fuglsang-Frederiksen
Apr 1, 1995·Electroencephalography and Clinical Neurophysiology·L KiersD Cros
Feb 1, 1995·Electroencephalography and Clinical Neurophysiology·D SanderJ Klingelhöfer
Dec 12, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A G GuggisbergJ Mathis
Feb 22, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Soile KomssiRisto J Ilmoniemi
Feb 3, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M WeberM Nakajima
Jul 13, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·H R SiebnerB Conrad
Jul 13, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·N KoharaJ Kimura
Jan 22, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·V Di LazzaroJ C Rothwell
Oct 6, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·J D RollnikR Dengler
Feb 22, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Francesca DalpozzoAlain Maertens de Noordhout
Oct 12, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A InabaH Mizusawa
Jan 4, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·U Ziemann, M Hallett
Feb 3, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·T FurubayashiI Kanazawa
Feb 19, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·W MuellbacherM Hallett
Jun 23, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·K H HoK Mills
Jun 11, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M L ByrnesF L Mastaglia
Jun 11, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·P AshbyJ Rothwell
Mar 9, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S BestmannJ C Rothwell
Nov 19, 2004·Experimental Brain Research·Monica A PerezJens B Nielsen
Nov 24, 2004·Experimental Brain Research·Nobue Kobayashi IwataYoshikazu Ugawa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.