Electrical impedance of isolated amnion

Biophysical Journal
G A SilverG A Misrahy

Abstract

The electrical impedance of the guinea pig amniotic membrane was measured, under standardized conditions, over the frequency range of 20 to 7000 cycles/second. This impedance can be represented analytically by a simple frequency-dependent function which is precisely of the form of the Debye relaxation equation. The observed data exhibit a broad dispersion centered at a frequency of 1050 cycles/second and a narrow distribution of time constants centered about 152 microseconds, both effects being due to the polydisperse nature of amniotic tissue. If the narrow time-constant distribution is approximated by a single time constant, amnion impedance can be simulated by a simple electrical circuit of frequency-independent elements. The Maxwell-Wagner interfacial treatment, although successfully adapted for cell suspensions, is shown to lose its quantitative significance in the case of the tightly structured amnion. In addition, determinations were made on the chemical composition of amniotic fluid, fetal blood and urine, and maternal blood and urine; the DC potential across the amniotic membrane was also measured.

Citations

Jul 30, 1976·Radiation and Environmental Biophysics·J Krupa, J Terlecki
Jan 1, 1969·British Journal of Pharmacology·A W Cuthbert, E Painter

Related Concepts

Structure of Amnion
Amniotic Fluid Index
Blood Chemical Analysis
Plasma Membrane
Electric Conductivity
Electrophysiology (Science)
Fetal Structures
Cavia porcellus
Pregnancy, Animal
Urine

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