Electrical impedance tomography (EIT) for quantification of pulmonary edema in acute lung injury

Critical Care : the Official Journal of the Critical Care Forum
Constantin J C TrepteDaniel A Reuter

Abstract

Assessment of pulmonary edema is a key factor in monitoring and guidance of therapy in critically ill patients. To date, methods available at the bedside for estimating the physiologic correlate of pulmonary edema, extravascular lung water, often are unreliable or require invasive measurements. The aim of the present study was to develop a novel approach to reliably assess extravascular lung water by making use of the functional imaging capabilities of electrical impedance tomography. Thirty domestic pigs were anesthetized and randomized to three different groups. Group 1 was a sham group with no lung injury. Group 2 had acute lung injury induced by saline lavage. Group 3 had vascular lung injury induced by intravenous injection of oleic acid. A novel, noninvasive technique using changes in thoracic electrical impedance with lateral body rotation was used to measure a new metric, the lung water ratioEIT, which reflects total extravascular lung water. The lung water ratioEIT was compared with postmortem gravimetric lung water analysis and transcardiopulmonary thermodilution measurements. A significant correlation was found between extravascular lung water as measured by postmortem gravimetric analysis and electrical impedance to...Continue Reading

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Citations

Apr 2, 2016·Intensive Care Medicine·Antonio PesentiMichael Quintel
Jun 21, 2017·Physiological Measurement·Susana Aguiar SantosDaniel Teichmann
Jul 18, 2017·IEEE Transactions on Bio-medical Engineering·Andy Adler, Alistair Boyle
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Jul 13, 2017·Critical Care : the Official Journal of the Critical Care Forum·Johannes BickenbachMichael Dreher
Jul 28, 2019·Biomedical Engineering Online·Geuk Young JangEung Je Woo
Dec 12, 2017·International Journal of Biomedical Imaging·Abdalla SalamaRajprasad Rajkumar
Apr 5, 2019·Minerva anestesiologica·Francesco VasquesLuigi Camporota
Dec 15, 2020·Current Opinion in Critical Care·Gabriele ViaLuigi Camporota
Dec 31, 2018·Journal of Electrical Bioimpedance·Jakob OrschulikMarian Walter

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Methods Mentioned

BETA
bronchoalveolar
bronchoalveolar lavage
lavage

Software Mentioned

SigmaPlot

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