PMID: 6840985Jan 1, 1983

Electrical stimulation of the superior olivary complex can produce cortical evoked potential and behavioral discrimination correlates of pitch perception in the rat

The International Journal of Neuroscience
D R BerardL H Berger

Abstract

Patterned electrical stimulation of the superior olivary complex (SOC) which simulated the neural frequency following response (FFR) extracellular potential was used as a stimulus in behavioral frequency discrimination and cortical evoked potential studies. Behavioral judgments of SOC stimulation frequency were found to be as accurate as those obtained for 80 dB acoustic stimuli within the spectral band of the FFR (200 to 3800 Hz). Cortical evoked potentials elicited by acoustic and electrical stimulation of the SOC were then compared for preservation of waveform similarity. Frequency dependent similarity was observed in slow wave events elicited by stimuli with frequencies in the FFR band. A 3 msec time lag was found between acoustic and SOC stimulation produced waveforms which can be accounted for by forward stimulation of the auditory pathway. Our study supports the idea that integrated extracellular waveforms of the FFR index low frequency representations in the auditory brainstem, perhaps by selecting patches of SOC cell transmembrane potential changes. Because bilateral cochlear damage did not prevent behavioral discrimination of SOC electrical stimulation, feedback to the ear is not necessary for perceptual significance ...Continue Reading

References

Feb 1, 1975·Electroencephalography and Clinical Neurophysiology·J T MarshJ C Smith
Apr 1, 1977·Electroencephalography and Clinical Neurophysiology·H Sohmer, H Pratt
Sep 1, 1977·Electroencephalography and Clinical Neurophysiology·O YamadaK Kodera
Jul 1, 1979·Electroencephalography and Clinical Neurophysiology·C L Faingold, D M Caspary
Oct 1, 1978·Physiology & Behavior·W R Coleman, L H Berger
Nov 1, 1979·Audiology : Official Organ of the International Society of Audiology·I C Whitfield
Sep 1, 1975·Journal of Neurophysiology·G MoushegianJ S Gidda
Sep 18, 1970·Science·J T MarshJ C Smith
Sep 1, 1964·Journal of Neurophysiology·C TSUCHITANI, J C BOUDREAU

Citations

Feb 21, 2007·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Helané WahbehHeather Zwickey
Mar 29, 2007·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Helané WahbehDan Zajdel

Related Concepts

Acoustic Stimulation
Behavior, Animal
Insula of Reil
Complete Hearing Loss
Electric Stimulation Technique
Potentials, Event-Related
Olivary Nucleus
Pitch Discrimination
August Rats

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