Electroacupuncture for patients with refractory functional dyspepsia: A randomized controlled trial

Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society
Hui ZhengF-R Liang

Abstract

To test the efficacy of electroacupuncture for patients with refractory functional dyspepsia (FD). A 24-week, 2-arm, single-blind, randomized controlled trial was conducted at three hospitals in China. Patients with refractory FD were randomly assigned to receive 20 sessions of authentic or sham electroacupuncture in a treatment duration of 4 weeks. The primary outcome was complete absence of dyspeptic symptoms at 16 weeks after initiation of acupuncture (week 16). The secondary outcomes included adequate relief of dyspeptic symptoms, Leeds Dyspepsia Questionnaire (LDQ), Nepean Dyspepsia Index (NDI), and adverse events. Intention-to-treat analysis was performed. Two hundred patients were included, of which 196 (98%) completed follow-up data at week 24. At week 16, 17 (17%) patients in the authentic electroacupuncture group vs 6 (6%) patients in the sham group achieved the primary outcome (P = .014). Sixty-two (62%) patients had adequate relief in the authentic electroacupuncture group, as compared to 22 (22%) in the sham group (P = .001). The scores of LDQ and NDI were significantly improved in both groups at week 16, and patients in the authentic electroacupuncture group have more improvements (LDQ, mean difference, -2.2, 95% ...Continue Reading

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Citations

Jun 16, 2018·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J D Z ChenJ Yin
May 23, 2019·Journal of Gastroenterology and Hepatology·Vincent Chi Ho ChungJustin Che Yuen Wu
Feb 8, 2020·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Jian-Feng TuCun-Zhi Liu
Feb 13, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Yu WangCun-Zhi Liu
Mar 30, 2019·Alimentary Pharmacology & Therapeutics·Imke MasuyJan Tack
May 19, 2020·Annals of Internal Medicine·Jing-Wen YangCun-Zhi Liu
Nov 19, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Pengfan LiChunxiang Fan
Oct 30, 2020·Journal of Clinical Gastroenterology·Stefano RabittiDora Colussi
Aug 4, 2021·Journal of Gastroenterology and Hepatology·Xi-Yang WangGuo-Ming Shen
Sep 30, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Lucas WautersFrank Zerbib
Oct 30, 2021·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Dan WangHongxing Zhang

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