Electrocardiographic and echocardiographic findings in muscular dystrophy patients with heart failure

Heart and Vessels
Masataka OgisoEiji Isozaki

Abstract

Cardiac involvement in muscular dystrophy (MD) is known to cause heart failure (HF). However, little is known about the differences in electrocardiographic and echocardiographic findings between MD patients with and without the experience of hospitalization for HF. We retrospectively identified 95 MD patients (mean age at diagnosis of MD 41.1 ± 18.7 years; males 64.2%), including nine (9.4%) patients who were hospitalized for HF (the HF group) and 86 (90.6%) patients who were not (the non-HF group) during the follow-up period (16.7 ± 12.2 years). The HF group had a significantly wider QRS duration (126.0 ± 37.6 vs. 98.1 ± 16.7 ms, p < 0.001) and QTc interval (454.6 ± 50.5 vs. 409.5 ± 23.6 ms, p < 0.001) at the time of HF hospitalization than the non-HF group. The HF group also had a significantly lower left ventricular (LV) ejection fraction (35.4 ± 19.2 vs. 62.5 ± 11.3%, p < 0.001) and significantly larger diastolic LV dimension (64 ± 2 vs. 45 ± 1 mm, p < 0.001) and left atrial diameter (38 ± 12 vs. 29 ± 6 mm, p = 0.003) at the time of HF hospitalization than the non-HF group. In the HF group, the QRS duration was significantly wider at the time of HF hospitalization than at the initial electrocardiogram before the development...Continue Reading

References

Mar 1, 1990·International Journal of Cardiology·G NigroR J Bain
Jul 1, 1994·American Heart Journal·Y S OrlovC A Jay
Oct 1, 1996·Journal of the Neurological Sciences·C AngeliniG A Danieli
Jun 8, 2000·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·A A CantorR Ilia
Mar 7, 2002·Lancet·Alan E H Emery
Sep 27, 2005·The American Journal of Cardiology·Markku S Nieminen, Veli-Pekka Harjola
Dec 7, 2007·Brain : a Journal of Neurology·Emma J GroenKatharine M D Bushby
Oct 9, 2008·The Canadian Journal of Cardiology·Josef Finsterer, Claudia Stöllberger
Oct 25, 2011·Rinshō shinkeigaku = Clinical neurology·Tsuyoshi MatsumuraSaburo Sakoda
Nov 21, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
Jun 14, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
Feb 4, 2014·Journal of Cardiac Failure·Juan Luis Bonilla-PalomasAntonia Villar-Ráez
Sep 4, 2015·The New England Journal of Medicine·Christian TemplinThomas F Lüscher
May 28, 2016·Journal of the American College of Cardiology·Forum Kamdar, Daniel J Garry
Aug 9, 2016·Muscle & Nerve·Madoka Mori-YoshimuraMiho Murata
Aug 20, 2016·International Journal of Cardiology·Giuseppina De BenedittisCesare de Gregorio
Sep 7, 2016·International Heart Journal·Koichi KimuraMasao Daimon
Dec 6, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Tetsuo YamaguchiMorimasa Takayama

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.